SCHEMBL217962

SCHEMBL217962

CC1=CC[C]=C1c1ccc(C)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NISCH Q9Y2I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215379 0.83 ALDH1A1 (0.33) ACHEALDH1A1LMNA
SCHEMBL21409695 0.81 ALDH1A1 (0.33) ACHETDP1ALDH1A1SMN1; SMN2
SCHEMBL2965730 0.64 ALDH1A1 (0.36) TDP1NPC1RAB9AALDH1A1LMNA
SCHEMBL18661495 0.63 ACHE (0.73) ACHETDP1ALDH1A1LMNA
SCHEMBL3287696 0.63 ACHE (0.73) ACHETDP1ALDH1A1LMNA
SCHEMBL197731 0.63 ACHE (0.73) ACHETDP1ALDH1A1LMNA
SCHEMBL217562 0.63
SCHEMBL31498547 0.60 ACHE (0.67) ACHETDP1ALDH1A1LMNA
SCHEMBL31591282 0.60 ACHE (0.67) ACHETDP1ALDH1A1LMNA
Water SCHEMBL3680095 0.60 ACHE (0.67) ACHETDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-7214747-B2 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-08 US disclosed
US-7214746-B2 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-08 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 ACHE 4220/4885TDP1 3673/4885NPC1 3144/4885
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization PYM1, ZNF207, POLL ACHE 3565/4885TDP1 3496/4885NPC1 4195/4885
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ACHE 2031/4885TDP1 4183/4885NPC1 4083/4885
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 ACHE 4524/4885TDP1 4547/4885NPC1 2433/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 ACHE 3187/4885TDP1 3268/4885NPC1 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.