SCHEMBL21798713

SCHEMBL21798713

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6cc(-n7c8ccccc8c8ccccc87)ccc65)c4)n3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.46
▸ ATM Q13315 2/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ RAC2 P15153 1/20 0.40
▸ RAC3 P60763 1/20 0.40
▸ CDC42 P60953 1/20 0.40
▸ RAC1 P63000 1/20 0.40
▸ PTGER4 P35408 1/20 0.37
▸ MEN1 O00255 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HPGD P15428 2/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ ABCG2 Q9UNQ0 4/20 0.36
▸ GAA P10253 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ PDE10A Q9Y233 1/20 0.35
▸ AVPR1A P37288 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24677079 1.00 KDM4E (0.46) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24677397 0.97 KDM4E (0.44) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24677393 0.97 L3MBTL1 (0.50) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24677430 0.97 L3MBTL1 (0.50) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL15786001 0.97 L3MBTL1 (0.49) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL15248676 0.97 L3MBTL1 (0.49) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL15212954 0.97 L3MBTL1 (0.49) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24677395 0.97 L3MBTL1 (0.49) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL15786015 0.97 L3MBTL1 (0.49) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL19041775 0.96 KDM4E (0.42) KDM4EATML3MBTL1RAC2RAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-06-12 — — US disclosed
US-12319653-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2025-06-03 — — US disclosed
US-20240199549-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-20 — — US disclosed
US-11939293-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-03-26 — — US disclosed
US-20230292539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
EP-4231804-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-08-23 — — EP disclosed
US-20230105380-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-06 — — US disclosed
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 — — US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 — — US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 — — US disclosed
US-20200079735-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM KDM4E 3594/4885ATM 1277/4885L3MBTL1 1135/4885
US-20200079735-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, L1CAM, EPCAM KDM4E 3594/4885ATM 1277/4885L3MBTL1 1135/4885
US-20250188031-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, OR10J3, ETV6 KDM4E 2313/4885ATM 1582/4885L3MBTL1 1692/4885
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSGEP KDM4E 2859/4885ATM 2960/4885L3MBTL1 1468/4885
US-12319653-B2 Organic electroluminescent materials and devices PIEZO1, OR10J3, LEF1 KDM4E 2489/4885ATM 1608/4885L3MBTL1 1874/4885
US-20240199549-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, OR10J3, LEF1 KDM4E 2489/4885ATM 1608/4885L3MBTL1 1874/4885
US-11939293-B2 Organic electroluminescent materials and devices OR10J3, L1CAM, EPCAM KDM4E 3385/4885ATM 2098/4885L3MBTL1 1370/4885
US-20230105380-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OR10J3, L1CAM, EPCAM KDM4E 3385/4885ATM 2098/4885L3MBTL1 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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