SCHEMBL2179948

SCHEMBL2179948

FC(F)(F)Sc1cc[c]cn1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1036554 0.71
SCHEMBL2895353 0.71 HAO1 (0.47) ALDH1A1
SCHEMBL2901251 0.68 PTPRZ1 (0.44) KDM4EALDH1A1TDP1
SCHEMBL75331 0.67 TRPV4 (0.41)
SCHEMBL25341276 0.67 PTPRZ1 (0.32)
SCHEMBL25340256 0.67 KDM4E (0.30) KDM4EALDH1A1TDP1
SCHEMBL3751147 0.67
SCHEMBL145124 0.66 ALDH1A1 (0.52) KDM4EALDH1A1TDP1
SCHEMBL1037031 0.65 SMN1; SMN2 (0.37) ALDH1A1
SCHEMBL1034623 0.65 HPGD (0.43) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105531265-B Pesticidal compounds 巴斯夫欧洲公司 2018-07-20 CN claimed
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP claimed
US-9497970-B2 Pesticide compounds BASF SE (DE) 2016-11-22 US claimed
US-20160157491-A1 Pesticide Compounds BASF SE (DE) 2016-06-09 US claimed
EP-3022185-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2016-05-25 EP claimed
CN-105531265-A Pesticidal compounds BASF SE 2016-04-27 CN claimed
WO-2015007682-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2015-01-22 WO claimed
EP-3514155-B1 HETEROCYCLIC COMPOUND, AND HARMFUL-ARTHROPOD-CONTROLLING AGENT CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2021-06-09 EP disclosed
US-10721929-B2 Heterocyclic compound and harmful-arthropod-controlling agent containing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-28 US disclosed
US-20190223436-A1 HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING AGENT CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-25 US disclosed
EP-3514155-A1 HETEROCYCLIC COMPOUND, AND HARMFUL-ARTHROPOD-CONTROLLING AGENT CONTAINING SAME Sumitomo Chemical Company, Limited (JP) 2019-07-24 EP disclosed
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP disclosed
US-9497970-B2 Pesticide compounds BASF SE (DE) 2016-11-22 US disclosed
US-20160157491-A1 Pesticide Compounds BASF SE (DE) 2016-06-09 US disclosed
US-20110166162-A1 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests BASF SE (DE) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157491-A1 Pesticide Compounds C1R, C1S, CBR3 KDM4E 3731/4885ALDH1A1 2336/4885TDP1 2862/4885
US-20110166162-A1 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests GLRX3, CBR3, PRDX1 KDM4E 4261/4885ALDH1A1 2095/4885TDP1 4169/4885
US-20190223436-A1 HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING AGENT CONTAINING SAME OXER1, TAAR1, NR1D1 KDM4E 3909/4885ALDH1A1 988/4885TDP1 3775/4885
US-10721929-B2 Heterocyclic compound and harmful-arthropod-controlling agent containing same OXER1, TAAR1, NR1D1 KDM4E 3909/4885ALDH1A1 988/4885TDP1 3775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.