SCHEMBL21799807

SCHEMBL21799807

Nc1ccc(NCC2CCCCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.46
APP P05067 1/20 0.44
EPHX1 P07099 5/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 2/20 0.43
ALDH3A1 P30838 1/20 0.43
AOC1 P19801 1/20 0.41
AOC3 Q16853 1/20 0.41
EPHX2 P34913 1/20 0.41
KDM4C Q9H3R0 1/20 0.38
S1PR1 P21453 1/20 0.37
LDLR P01130 1/20 0.37
ITK Q08881 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GRM4 Q14833 1/20 0.37
ASPH Q12797 1/20 0.37
KDM8 Q8N371 1/20 0.37
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10187375 0.90 PTGER4 (0.42) APPEPHX1GAARAB9AALDH1A1
SCHEMBL2935193 0.90 PTGER4 (0.42) APPEPHX1GAARAB9AALDH1A1
Hydrochloric Acid SCHEMBL5451018 0.88 PTGER4 (0.41) APPEPHX1GAARAB9AALDH1A1
SCHEMBL2928230 0.87 NFE2L2 (0.38) NFE2L2APPEPHX1GAARAB9A
Hydrochloric Acid SCHEMBL5442441 0.85 NFE2L2 (0.37) NFE2L2APPEPHX1GAARAB9A
SCHEMBL11934756 0.83 PTGER4 (0.38) APPEPHX1GAARAB9AALDH1A1
SCHEMBL13438646 0.83 PTGER4 (0.38) APPEPHX1GAARAB9AALDH1A1
SCHEMBL23173423 0.81 CARM1 (0.38) APPGAAALDH1A1ALDH3A1CARM1
SCHEMBL20567955 0.81 RAB9A (0.53) EPHX1RAB9AALDH1A1ALDH3A1AOC1
SCHEMBL22414314 0.81 NPC1 (0.47) EPHX1RAB9AALDH1A1ALDH3A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
US-20230117592-A1 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2023-04-20 US disclosed
EP-4081199-A2 LIPOXYGENASE INHIBITORS SRI International (US) 2022-11-02 EP disclosed
CN-110603273-B Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2022-10-14 CN disclosed
US-11124593-B2 Modified block copolymer, method for producing modified block copolymer, and resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
WO-2021133689-A2 LIPOXYGENASE INHIBITORS SRI INTERNATIONAL (US) 2021-07-01 WO disclosed
US-20200199282-A1 Modified Block Copolymer, Method for Producing Modified Block Copolymer, and Resin Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-06-25 US disclosed
EP-3623398-A1 MODIFIED BLOCK COPOLYMER, METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER, AND RESIN COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2020-03-18 EP disclosed
CN-110603273-A Modified block copolymer, method for producing modified block copolymer, and resin composition 旭化成株式会社 2019-12-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117592-A1 LIPOXYGENASE INHIBITORS ALOX15B, ALOX12, ALOX5 NFE2L2 33/4885APP 348/4885EPHX1 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.