Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419788 | 0.91 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2869922 | 0.89 | TSHR (0.48) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL28417952 | 0.87 | TSHR (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL27483123 | 0.80 | ZDHHC20 (0.38) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL336794 | 0.80 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL10416603 | 0.79 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL475906 | 0.78 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL4126549 | 0.78 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL19971208 | 0.77 | BBOX1 (0.42) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL25324391 | 0.76 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795255-B2 | Method for producing paper or cardboard | SOLENIS TECHNOLOGIES, L.P. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20220033555-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) | 2022-02-03 | — | — | US | disclosed |
| EP-3850020-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | Solenis Technologies Cayman, L.P. (KY) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020053379-A1 | METHOD FOR PRODUCING PAPER OR CARDBOARD | SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) | 2020-03-19 | — | — | WO | disclosed |