Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417952 | 0.98 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL21801685 | 0.89 | ZDHHC20 (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.82 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28419788 | 0.82 | ZDHHC20 (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL475906 | 0.80 | ZDHHC20 (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL9451758 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL1473578 | 0.78 | ALDH1A1 (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL10416603 | 0.78 | ZDHHC20 (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1200572 | 0.78 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL475933 | 0.77 | ZDHHC20 (0.58) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428684-B2 | Addition of zwitterionic surfactant to water soluble polymer to increase the stability of the polymers in aqueous solutions containing salt and/or surfactants | RHODIA OPERATION (FR) | 2016-08-30 | — | — | US | claimed |
| US-12577452-B2 | Surfactants for oil and gas production | ADVANSIX RESINS & CHEMICALS LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-20250289995-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-09-18 | — | — | US | disclosed |
| US-12351756-B2 | Surfactants for oil and gas production | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-07-08 | — | — | US | disclosed |
| US-20250051633-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2025034846-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| US-12221579-B2 | Formulation for the recovery of hydrocarbons including a surfactant system | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-11 | — | — | US | disclosed |
| US-20240376371-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2024-11-14 | — | — | US | disclosed |
| US-20240368455-A1 | BRANCHED AMINO ACID SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2024-11-07 | — | — | US | disclosed |
| US-12071588-B2 | Branched amino acid surfactants for oil and gas production | ADVANSIX RESINS & CHEMICALS LLC (US) | 2024-08-27 | — | — | US | disclosed |
| EP-2205827-B1 | ADDITION OF NONIONIC SURFACTANTS TO WATER SOLUBLE BLOCK COPOLYMERS TO INCREASE THE STABILITY OF THE COPOLYMER IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | SOLVAY USA INC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9428684-B2 | Addition of zwitterionic surfactant to water soluble polymer to increase the stability of the polymers in aqueous solutions containing salt and/or surfactants | RHODIA OPERATION (FR) | 2016-08-30 | — | — | US | disclosed |
| US-7789160-B2 | Addition of nonionic surfactants to water soluble block copolymers to increase the stability of the copolymer in aqueous solutions containing salt and/or surfactants | RHODIA INC. (US) | 2010-09-07 | — | — | US | disclosed |
| EP-2205827-A2 | ADDITION OF NONIONIC SURFACTANTS TO WATER SOLUBLE BLOCK COPOLYMERS TO INCREASE THE STABILITY OF THE COPOLYMER IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | Rhodia, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| EP-2205826-A2 | ADDITION OF ZWITTERIONIC SURFACTANT TO WATER SOLUBLE POLYMER TO INCREASE THE STABILITY OF THE POLYMERS IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | Rhodia, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009058590-A2 | ADDITION OF NONIONIC SURFACTANTS TO WATER SOLUBLE BLOCK COPOLYMERS TO INCREASE THE STABILITY OF THE COPOLYMER IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | RHODIA INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058589-A2 | ADDITION OF ZWITTERIONIC SURFACTANT TO WATER SOLUBLE POLYMER TO INCREASE THE STABILITY OF THE POLYMERS IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | RHODIA INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090107681-A1 | ADDITION OF NONIONIC SURFACTANTS TO WATER SOLUBLE BLOCK COPOLYMERS TO INCREASE THE STABILITY OF THE COPOLYMER IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | RHODIA INC. (US) | 2009-04-30 | — | — | US | disclosed |
| US-20090111716-A1 | ADDITION OF ZWITTERIONIC SURFACTANT TO WATER SOLUBLE POLYMER TO INCREASE THE STABILITY OF THE POLYMERS IN AQUEOUS SOLUTIONS CONTAINING SALT AND/OR SURFACTANTS | RHODIA INC. (US) | 2009-04-30 | — | — | US | disclosed |
| US-4390659-A | Method for the preparation of quaternary carboxamide polymers | THE DOW CHEMICAL COMPANY (US) | 1983-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351756-B2 | Surfactants for oil and gas production | DEGS1, FASN, SGMS1 | TSHR 2097/4885ALDH1A1 4858/4885MAPK1 4438/4885 |
| US-12577452-B2 | Surfactants for oil and gas production | SLC6A9, SFN, SLC6A12 | TSHR 1843/4885ALDH1A1 4701/4885MAPK1 1187/4885 |
| US-20250289995-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | DEGS1, FASN, SGMS1 | TSHR 2097/4885ALDH1A1 4858/4885MAPK1 4438/4885 |
| US-20250051633-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | DEGS1, FASN, SGMS1 | TSHR 2097/4885ALDH1A1 4858/4885MAPK1 4438/4885 |
| US-20240376371-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | DEGS1, FASN, SGMS1 | TSHR 2097/4885ALDH1A1 4858/4885MAPK1 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.