Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126549 | 0.98 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL25324391 | 0.96 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Chloromethane SCHEMBL28028247 | 0.95 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Acrylic Acid SCHEMBL396773 | 0.93 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Acrylamide SCHEMBL28870529 | 0.93 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL29142619 | 0.87 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28470855 | 0.86 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.85 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL28180741 | 0.85 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2551112 | 0.84 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595396-B2 | Acid resistant filter media | ENTEGRIS, INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-20260081162-A1 | Polymer Coating Process For Electrode Assemblies Incorporating Ion Exchange Materials | ZELOS ENERGY LTD (US) | 2026-03-19 | — | — | US | claimed |
| US-20260045558-A1 | Battery Separator with Ion Exchange Materials | ZELOS ENERGY LTD (US) | 2026-02-12 | — | — | US | claimed |
| US-12531244-B2 | Polymer coating process for electrode assemblies incorporating ion exchange materials | ZELOS ENERGY LTD. (US) | 2026-01-20 | — | — | US | claimed |
| CN-115969726-B | Multi-effect composition, shampoo and preparation method thereof | 广州市芙缇化妆品有限公司 | 2025-06-24 | — | — | CN | claimed |
| WO-2025040784-A1 | WATER-SOLUBLE POLYMER AS BATTERY BINDING MATERIAL | SNF GROUP (FR) | 2025-02-27 | — | — | WO | claimed |
| EP-4121466-B1 | NOVEL WATER-SOLUBLE POLYMER COMPLEXES IN THE FORM OF AN INVERSE EMULSION AND USES THEREOF | SNF GROUP (FR) | 2024-10-23 | — | — | EP | claimed |
| EP-4429802-A1 | MEMBRANE FOR REMOVING ANIONIC MATERIALS | Entegris, Inc. (US) | 2024-09-18 | — | — | EP | claimed |
| US-20240132644-A1 | MACROMONOMER, METHOD FOR OBTAINING SAME AND COPOLYMER CONTAINING SAME | SNF GROUP (FR) | 2024-04-25 | — | — | US | claimed |
| US-11834559-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2023-12-05 | — | — | US | claimed |
| US-6485651-B1 | Quick inverting liquid flocculant | ONDEO NALCO COMPANY | 2002-11-26 | — | — | US | claimed |
| WO-2002079099-A1 | QUICK INVERTING LIQUID FLOCCULANT | ONDEO NALCO COMPANY (US) | 2002-10-10 | — | — | WO | claimed |
| WO-2001051707-A1 | THE USE OF INORGANIC SOLS IN THE PAPERMAKING PROCESS | CALGON CORPORATION (US) | 2001-07-19 | — | — | WO | claimed |
| EP-0900299-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BetzDearborn Inc (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0900299-A4 | — | — | 1999-03-10 | — | — | EP | claimed |
| WO-1997044519-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BETZDEARBORN INC. (US) | 1997-11-27 | — | — | WO | claimed |
| US-5647956-A | Cellulosic, modified lignin and cationic polymer composition and process for making improved paper or paperboard | CALGON CORPORATION (US) | 1997-07-15 | — | — | US | claimed |
| US-5567277-A | IMPROVING DRAINAGE, RETENTION, FORMATION BY MIXING A BLEND OF A HIGH MOLECULAR WEIGHT COPOLYMER COMPRISING (METH-) ACRYLOYLOXY- OR (METH-)ACRYLAMIDO ALKYL TRIMETHYL AMMONIUM CHLORIDE AND ACRYLAMIDE | CALGON CORPORATION (US) | 1996-10-22 | — | — | US | claimed |
| EP-0628658-A1 | Cellulosic, modified lignin and cationic polymer composition and process for making improved paper or paperboard | CALGON CORPORATION (US) | 1994-12-14 | — | — | EP | claimed |
| US-4293427-A | (METH)ACRYLAMIDE-(METH)ACRYLAMIDOSULFONIC ACID COPOLYMER OPTIONALLY CROSSLINKED | MILCHEM INCORPORATED (US) | 1981-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260081162-A1 | Polymer Coating Process For Electrode Assemblies Incorporating Ion Exchange Materials | NES, SLC8A1, NCS1 | ZDHHC20 3271/4885ZDHHC2 2503/4885TSHR 4491/4885 |
| US-20260045558-A1 | Battery Separator with Ion Exchange Materials | CACNA2D3, CACNA2D2, CACNA2D1 | ZDHHC20 1869/4885ZDHHC2 1351/4885TSHR 2824/4885 |
| US-12531244-B2 | Polymer coating process for electrode assemblies incorporating ion exchange materials | NCSTN, GNE, NCS1 | ZDHHC20 3951/4885ZDHHC2 3362/4885TSHR 3982/4885 |
| US-12595396-B2 | Acid resistant filter media | SDC2, F7, SDC1 | ZDHHC20 2994/4885ZDHHC2 2683/4885TSHR 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.