SCHEMBL21802151

SCHEMBL21802151

O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ccc(Cl)cc2Cl)CC1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.70
DRD3 P35462 3/20 0.70
DRD4 P21917 2/20 0.70
HTR1A P08908 5/20 0.62
ALDH1A1 P00352 2/20 0.60
MEN1 O00255 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
ALOX12 P18054 1/20 0.60
ADRA1D P25100 1/20 0.60
HTR7 P34969 1/20 0.60
ADRA1A P35348 1/20 0.60
ADRA1B P35368 1/20 0.60
KMT2A Q03164 1/20 0.60
HIF1A Q16665 1/20 0.60
HSD17B10 Q99714 1/20 0.60
HTR2A P28223 1/20 0.60
KDM4E B2RXH2 1/20 0.59
GLA P06280 1/20 0.59
HPGD P15428 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21802161 0.89 DRD2 (0.66) DRD2DRD3DRD4HTR1AADRA1D
SCHEMBL21802140 0.87 DRD2 (0.85) DRD2DRD3DRD4HTR1AALDH1A1
SCHEMBL2315895 0.87 ADRA1D (0.73) DRD2DRD3DRD4HTR1AALDH1A1
Hydrochloric Acid SCHEMBL9987656 0.86 ADRA1D (0.72) DRD2DRD3DRD4HTR1AALDH1A1
SCHEMBL2510367 0.84 ADRA1D (0.73) DRD2DRD3DRD4HTR1AALDH1A1
SCHEMBL21802143 0.84 HTR1A (0.76) DRD2HTR1AHTR7HTR2A
SCHEMBL21802068 0.83 HTR1A (0.80) DRD2DRD3HTR1AADRA1DHTR7
SCHEMBL4917290 0.82 DRD2 (1.00) DRD2DRD3DRD4HTR1AALDH1A1
SCHEMBL6771089 0.82 DRD2 (0.76) DRD2DRD3HTR1AALDH1A1MEN1
SCHEMBL10835969 0.81 HTR1A (0.76) DRD2HTR1AHTR7HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319659-B2 Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof SHENZHEN LINGLAN BIO-PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) 2025-06-03 US disclosed
US-20200087264-A1 NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF Shenzhen City Linglan Bio-Pharmaceutical Technology Co., Ltd (CN) 2020-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087264-A1 NOVEL SELECTIVE LIGAND FOR DOPAMINE D3 RECEPTOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF DRD3, DRD2, PRLHR DRD2 2/4885DRD3 1/4885DRD4 7/4885
US-12319659-B2 Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof DRD3, DRD2, PRLHR DRD2 2/4885DRD3 1/4885DRD4 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.