Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505165 | 1.00 | CYP2A6 (0.48) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL21490690 | 0.91 | CYP2A6 (0.41) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL10479554 | 0.80 | CYP2A6 (0.44) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL10479669 | 0.80 | CYP2A6 (0.44) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL9138633 | 0.78 | ESR1 (0.50) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL10479743 | 0.78 | ALDH1A1 (0.42) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL9137368 | 0.77 | KIF11 (0.41) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL2012822 | 0.75 | CHRNA7 (0.44) | CYP2A6ALDH1A1CYP1A2CYP3A4CHRNB2 | |
| SCHEMBL7032434 | 0.75 | CYP2A6 (0.39) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL30272173 | 0.75 | CYP2A6 (0.39) | CYP2A6ALDH1A1CYP1A2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174502-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2023-06-08 | — | — | US | disclosed |
| EP-3792270-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | Samsung Electronics Co., Ltd. (KR) | 2021-03-17 | — | — | EP | disclosed |
| CN-109983022-A | As the chromans of mGluR2 negativity allosteric modulators, heterochromatic full and dihydroisobenzofuran derivative, composition and application thereof | 默沙东公司 | 2019-07-05 | — | — | CN | disclosed |
| US-9818551-B2 | Additive for electrolytic composition, electrolytic composition using this additive, and dye-sensitized solar cell | ADEKA CORPORATION (JP) | 2017-11-14 | — | — | US | disclosed |
| US-9818551-B2 | Additive for electrolytic composition, electrolytic composition using this additive, and dye-sensitized solar cell | ADEKA CORPORATION (JP) | 2017-11-14 | — | — | US | disclosed |
| US-9818551-B2 | Additive for electrolytic composition, electrolytic composition using this additive, and dye-sensitized solar cell | ADEKA CORPORATION (JP) | 2017-11-14 | — | — | US | disclosed |
| EP-2618420-B1 | ADDITIVE FOR USE IN DYE-SENSITIZED SOLAR CELL | ADEKA CORP (JP) | 2016-12-07 | — | — | EP | disclosed |
| CN-105968142-A | Organometallic compound and organic light-emitting device including the same | 三星电子株式会社 | 2016-09-28 | — | — | CN | disclosed |
| EP-2618420-A1 | ADDITIVE FOR ELECTROLYTIC COMPOSITION, ELECTROLYTIC COMPOSITION USING THIS ADDITIVE, AND DYE-SENSITIZED SOLAR CELL | Adeka Corporation (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20130161555-A1 | ADDITIVE FOR ELECTROLYTIC COMPOSITION, ELECTROLYTIC COMPOSITION USING THIS ADDITIVE, AND DYE-SENSITIZED SOLAR CELL | ADEKA CORPORATION (JP) | 2013-06-27 | — | — | US | disclosed |
| EP-2160385-A1 | 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES | Novogen Research Pty. Ltd. (AU) | 2010-03-10 | — | — | EP | disclosed |
| US-20090176781-A1 | Acetylenic Heteroaryl Compounds | ARIAD PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | disclosed |
| WO-2009003229-A1 | 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES | NOVOGEN RESEARCH PTY LTD (AU) | 2009-01-08 | — | — | WO | disclosed |
| US-20030139600-A1 | 2-pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL CO., LTD. | 2003-07-24 | — | — | US | disclosed |
| US-6548673-B1 | Alkylation using transition metal complex catalyst; purified by acid/base extraction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6531602-B2 | Desilylation of a 2-pyridylsilane to form an alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020165397-A1 | 2-Pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL CO., LTD. | 2002-11-07 | — | — | US | disclosed |
| EP-1035125-A2 | 2-Pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |
| US-4857521-A | Trialkylsilyl pyridinium cephalosporin antibiotics | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0231124-A2 | Cephalosporin derivatives, salts thereof, process for their manufacture, and pharmaceutical agents comprising them | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165397-A1 | 2-Pyridylsilane, processes for producing and using the same | H1-0, RIOK2, H1-4 | CYP2A6 1139/4885ALDH1A1 497/4885CYP1A2 363/4885 |
| US-20090176781-A1 | Acetylenic Heteroaryl Compounds | NAT1, AADAC, ACACA | CYP2A6 61/4885ALDH1A1 148/4885CYP1A2 32/4885 |
| US-20030139600-A1 | 2-pyridylsilane, processes for producing and using the same | H1-0, H1-4, H1-2 | CYP2A6 1185/4885ALDH1A1 479/4885CYP1A2 390/4885 |
| US-20230174502-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | PAX2, PAX3, HPRT1 | CYP2A6 4628/4885ALDH1A1 4415/4885CYP1A2 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.