Cyclopropane

Cyclopropane

SCHEMBL21806702

C1CC1.C=C(C)C(=O)NN

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 3/20 0.36
RXFP1 Q9HBX9 1/20 0.35
TGFBR1 P36897 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
THPO P40225 1/20 0.32
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249544 0.92
Hydrochloric Acid SCHEMBL28017818 0.89
Oxalic Acid SCHEMBL10896077 0.82 TDP1 (0.39) TDP1ALDH1A1RXFP1TGFBR1KDM4E
SCHEMBL1905147 0.71 TDP1 (0.80) TDP1ALDH1A1TSHRLMNA
Cyclohexane SCHEMBL347610 0.71 TDP1 (0.80) TDP1ALDH1A1TSHRLMNA
Cyclohexane SCHEMBL2887999 0.71 TDP1 (0.80) TDP1ALDH1A1TSHRLMNA
Cyclopropane SCHEMBL10359668 0.70 ALDH1A1 (0.35) TDP1ALDH1A1RXFP1TGFBR1KDM4E
Cyclohexane SCHEMBL10642803 0.69 TDP1 (0.75) TDP1ALDH1A1LMNA
SCHEMBL25316068 0.67 ALDH1A1 (0.50) TDP1ALDH1A1RXFP1TGFBR1KDM4E
Methacrylic Acid SCHEMBL4134914 0.67 TDP1 (0.44) TDP1ALDH1A1TGFBR1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210403625-A1 BORONIC ACID POLYMERS AND METHODS OF USE GLYSCEND, INC. 2021-12-30 US disclosed
EP-3852768-A1 BORONIC ACID POLYMERS AND METHODS OF USE Glyscend, Inc. (US) 2021-07-28 EP disclosed
WO-2020061430-A1 BORONIC ACID POLYMERS AND METHODS OF USE GLYSCEND, INC. (US) 2020-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403625-A1 BORONIC ACID POLYMERS AND METHODS OF USE SLC10A2, SI, PYGL TDP1 899/4885ALDH1A1 3561/4885RXFP1 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.