Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153196 | 0.78 | CES2 (0.42) | ALDH1A1KDM4ECES2CES1MEN1 | |
| SCHEMBL29782139 | 0.77 | HPGD (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL25108748 | 0.77 | CES2 (0.37) | ALDH1A1KDM4EGAACES2CES1 | |
| SCHEMBL25108905 | 0.77 | CES2 (0.37) | ALDH1A1KDM4EGAACES2CES1 | |
| SCHEMBL2651614 | 0.77 | HPGD (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL23025106 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EGAACES2CES1 | |
| SCHEMBL14638925 | 0.73 | TAS1R3 (0.38) | ALDH1A1KDM4EGAATAS1R3TAS1R1 | |
| SCHEMBL926435 | 0.71 | HPGD (0.44) | ALDH1A1KDM4ECES2CES1MEN1 | |
| SCHEMBL27154482 | 0.71 | RAB9A (0.44) | ALDH1A1KDM4EGAACES2CES1 | |
| SCHEMBL6152817 | 0.71 | CES2 (0.47) | GAACES2MAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065368-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| EP-3852790-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | Forma Therapeutics, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020061261-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065368-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | USP9X, USP19, USP39 | ALDH1A1 1794/4885KDM4E 576/4885GAA 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.