SCHEMBL2180736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4421469	0.87	PIK3C2B (0.45)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL4419245	0.86	NPC1 (0.46)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL2170676	0.85	LMNA (0.44)	GAAL3MBTL1NPC1RAB9AMAPT
	SCHEMBL4424484	0.84	LMNA (0.41)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL4421360	0.83	NPC1 (0.43)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL4422629	0.83	ALDH1A1 (0.41)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL2178940	0.83	HRH3 (0.47)	GAAMAPK1L3MBTL1NPC1RAB9A
	SCHEMBL4412123	0.83	L3MBTL1 (0.41)	GAAALOX15MAPK1L3MBTL1NPC1
	SCHEMBL2180733	0.83	NPC1 (0.50)	CYP2A13GAAALOX15MAPK1L3MBTL1
	SCHEMBL4413699	0.82	GAA (0.48)	GAAL3MBTL1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.