Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811052 | 1.00 | HSD11B1 (0.45) | HSD11B1TNKSPARP1PARP2LMNA | |
| SCHEMBL7183866 | 0.86 | HSD11B1 (0.47) | HSD11B1PARP1PARP2MAPT | |
| SCHEMBL7183859 | 0.86 | HSD11B1 (0.47) | HSD11B1PARP1PARP2MAPT | |
| SCHEMBL23236182 | 0.83 | HSD11B1 (0.47) | HSD11B1TNKSPARP1PARP2CHRM1 | |
| SCHEMBL23236178 | 0.83 | HSD11B1 (0.47) | HSD11B1TNKSPARP1PARP2CHRM1 | |
| SCHEMBL7191692 | 0.81 | ALDH1A1 (0.49) | HSD11B1HTTJAK2JAK3CHRM1 | |
| SCHEMBL23236167 | 0.80 | HSD11B1 (0.47) | HSD11B1TNKSPARP1PARP2OPRM1 | |
| SCHEMBL23236171 | 0.80 | HSD11B1 (0.47) | HSD11B1TNKSPARP1PARP2OPRM1 | |
| SCHEMBL7180238 | 0.77 | HSD11B1 (0.39) | HSD11B1TNKSJAK2JAK3GAA | |
| SCHEMBL7180232 | 0.77 | HSD11B1 (0.39) | HSD11B1TNKSJAK2JAK3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-07-08 | — | — | US | disclosed |
| EP-3808747-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020054788-A1 | IMIDAZOPYRIDINONE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | DHPS, EGLN3, P4HA1 | HSD11B1 216/4885TNKS 1673/4885PARP1 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.