Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216452 | 0.92 | ALDH1A1 (0.43) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL11049298 | 0.86 | ALDH1A1 (0.50) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL5445839 | 0.86 | ALDH1A1 (0.47) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL5445343 | 0.86 | TSHR (0.52) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL451538 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL5414893 | 0.82 | HSD11B1 (0.40) | ALDH1A1HSD11B1MAPTNPC1RAB9A | |
| SCHEMBL8629251 | 0.82 | HSD11B1 (0.49) | ALDH1A1LMNAGAAHSD11B1MEN1 | |
| SCHEMBL6140382 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL36543 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ACHELMNAGAAHSD11B1 | |
| SCHEMBL218044 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ACHELMNAGAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | claimed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | claimed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | claimed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ALDH1A1 3154/4885ACHE 3212/4885LMNA 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.