Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 11/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 9/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.35 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CCND2 | P30279 | 5/20 | 0.35 |
| ▸ | CCND3 | P30281 | 5/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181863 | 0.94 | GAA (0.39) | GAASMN1; SMN2HIF1ACA1CA2 | |
| SCHEMBL2182140 | 0.91 | ADORA2A (0.37) | GAAADORA2A | |
| SCHEMBL2181800 | 0.90 | SRC (0.36) | CDK4CDK6ADORA2ACCND1CCNA2 | |
| SCHEMBL2182344 | 0.88 | ALDH1A1 (0.42) | SMN1; SMN2CA2CA9 | |
| SCHEMBL2180599 | 0.85 | CA1 (0.42) | CA1CA2CA9 | |
| SCHEMBL2182971 | 0.85 | POLB (0.39) | ADORA2A | |
| SCHEMBL2182119 | 0.84 | CACNA1G (0.39) | GAASMN1; SMN2HIF1ACDK4RAD52 | |
| SCHEMBL2184891 | 0.84 | SRC (0.41) | GAAADORA2AFGFR1FGFR2FGFR4 | |
| SCHEMBL2182366 | 0.83 | ADORA2A (0.39) | CDK6ADORA2ACCND1CDK2CCNE1 | |
| SCHEMBL2182414 | 0.83 | ADORA2A (0.39) | CDK6ADORA2ACCND1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181524-A1 | PHARMACEUTICAL COMBINATION AND USE THEREOF | NATURAL MEDICINE INSTITUTE OF ZHEJIANG YANGSHENGTANG CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20110166144-A1 | Pyrimidotriazinediones and Pyrimidopyrimidinediones and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181524-A1 | PHARMACEUTICAL COMBINATION AND USE THEREOF | TCF4, TCF7L2, CTNNB1 | GAA 2804/4885SMN1; SMN2 2047/4885HIF1A 1000/4885 |
| US-20110166144-A1 | Pyrimidotriazinediones and Pyrimidopyrimidinediones and Methods of Using the Same | DPYD, TYMP, DHFR | GAA 1134/4885SMN1; SMN2 2741/4885HIF1A 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.