SCHEMBL21823219

SCHEMBL21823219

CC1=CC(=O)N(Cc2cccc(CN3C(=O)C=C(C)C3=O)c2)C1=O.CC1=CC(=O)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RGS4 P49798 2/20 0.40
KMT2A Q03164 8/20 0.38
MEN1 O00255 6/20 0.38
MAPT P10636 4/20 0.36
HPGD P15428 4/20 0.36
ALDH1A1 P00352 2/20 0.36
CMA1 P23946 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 3/20 0.34
MAPK1 P28482 3/20 0.34
POLB P06746 2/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
UBE2N P61088 1/20 0.33
PABPC1 P11940 1/20 0.33
ALOX15 P16050 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168682 0.87 RGS4 (0.49) RGS4KMT2AMEN1MAPTHPGD
SCHEMBL907301 0.76 RGS4 (0.64) RGS4KMT2AMEN1MAPTHPGD
SCHEMBL1133156 0.74 MGLL (0.50) RGS4CMA1
SCHEMBL21738352 0.73 KMT2A (0.41) RGS4KMT2AMEN1MAPTHPGD
SCHEMBL3677446 0.72 GSK3A (0.43) RGS4KMT2AMEN1MAPTALDH1A1
SCHEMBL1133468 0.70 PTGS1 (0.39) RGS4KMT2AMEN1MAPTHPGD
SCHEMBL1133216 0.70 PTGS1 (0.39) RGS4KMT2AMEN1MAPTHPGD
Diphenylmethane SCHEMBL10593665 0.70 CALM1 (0.44) KMT2AMEN1
Diphenylmethane SCHEMBL29204695 0.70 CALM1 (0.44) KMT2AMEN1
SCHEMBL28209189 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP disclosed
US-20210395420-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2021-12-23 US disclosed
EP-3861037-A1 RESIN COMPOSITION Cubicure GmbH (AT) 2021-08-11 EP disclosed
WO-2020070639-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2020-04-09 WO disclosed
EP-3632941-A1 RESIN COMPOSITION Cubicure GmbH (AT) 2020-04-08 EP disclosed