SCHEMBL907301

SCHEMBL907301

CC1=CC(=O)N(Cc2ccccc2)C1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RGS4 P49798 2/20 0.64
GSK3A P49840 1/20 0.55
GSK3B P49841 1/20 0.55
MGLL Q99685 1/20 0.55
ELANE P08246 3/20 0.53
F2 P00734 1/20 0.53
PLG P00747 1/20 0.53
CTSG P08311 1/20 0.53
CMA1 P23946 1/20 0.53
CTRC Q99895 1/20 0.53
CASP3 P42574 1/20 0.51
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ALDH1A1 P00352 4/20 0.46
APAF1 O14727 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
ALDH2 P05091 1/20 0.46
CHRM1 P11229 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133156 0.90 MGLL (0.50) RGS4GSK3AGSK3BMGLLELANE
SCHEMBL168682 0.87 RGS4 (0.49) RGS4GSK3AGSK3BMGLLELANE
SCHEMBL28170505 0.84 RGS4 (0.45) RGS4MGLLMEN1KMT2AALDH1A1
SCHEMBL29676946 0.83 PTGS1 (0.50) RGS4MGLLMEN1KMT2AMAPT
SCHEMBL1132983 0.83 PTGS1 (0.50) RGS4MGLLMEN1KMT2AMAPT
SCHEMBL24119845 0.82 GSK3A (0.58) RGS4GSK3AGSK3BMGLLCASP3
SCHEMBL24939705 0.82 PTGS1 (0.61) RGS4MEN1KMT2AALDH1A1MAPT
SCHEMBL9786685 0.81 RGS4 (0.68) RGS4GSK3AGSK3BMGLLELANE
SCHEMBL6139020 0.80 RGS4 (0.49) RGS4GSK3AGSK3BMGLLELANE
SCHEMBL28438474 0.80 GSK3A (0.60) RGS4GSK3AGSK3BMGLLCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986703-A Preparation method of heat-resistant low-pressure-change damping rubber part for automobile 奇瑞汽车股份有限公司 2024-05-07 CN claimed
CN-114805959-B Pre-dispersed rubber auxiliary master batch, preparation method and application thereof 山东华聚高分子材料有限公司 2024-01-26 CN claimed
CN-117203276-A Rubber composition, rubber-metal composite, tire, hose and crawler belt 株式会社普利司通 2023-12-08 CN claimed
CN-117136142-A Rubber mixtures containing N, N' -dialkyl-p-phenylenediamine 朗盛德国有限责任公司 2023-11-28 CN claimed
CN-116102794-A High-modulus high-temperature-resistant dynamic shear fatigue rubber composition for tire and preparation method thereof 广东粤港澳大湾区黄埔材料研究院 2023-05-12 CN claimed
CN-112625371-B Damping sucker composite material and preparation method thereof 宁波柯林斯橡塑科技有限公司 2022-10-14 CN claimed
CN-114805959-A Pre-dispersed rubber auxiliary master batch, preparation method and application thereof 山东华聚高分子材料有限公司 2022-07-29 CN claimed
CN-113004588-B Aircraft tire tread composition and preparation method thereof 广东粤港澳大湾区黄埔材料研究院 2022-07-05 CN claimed
CN-112852027-B Rubber composition, preparation method of rubber and hourglass spring 比亚迪股份有限公司 2022-05-13 CN claimed
CN-114450335-A Rubber composition, rubber-metal composite, tire, conveyor belt, hose, and crawler belt 株式会社普利司通 2022-05-06 CN claimed
EP-1911606-B1 Runflat tire GOODYEAR TIRE & RUBBER (US) 2010-05-19 EP claimed
WO-2009077420-A2 EPOXY CURING SYSTEM AND COATINGS OBTAINED THEREOF FLEXSYS HOLDING B.V. (NL) 2009-06-25 WO claimed
US-7549454-B2 radial medium truck tire; tensile strength, modulus retention, stiffness, fracture and tear resistance, reversion resistance; rubber and m-phenylenediamine bismaleimide and bis-(3-triethoxysilylpropyl)-tetrasulfide and 1,3-bis (citraconimido-methyl) benzene; no resorcinol resin, environmentally friendly THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-06-23 US claimed
US-20070155876-A1 Belt coat composition THE GOODYEAR TIRE & RUBBER COMPANY 2007-07-05 US claimed
EP-1803769-A2 Belt coat composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-07-04 EP claimed
EP-1125976-B1 Chafer rubber composition, and heavy duty pneumatic tyre using the chafer rubber composition SUMITOMO RUBBER IND (JP) 2005-11-09 EP claimed
EP-1211282-B1 Rubber mix comprising expanded layer silicates CONITECH HOLDING GMBH (DE) 2004-12-01 EP claimed
US-20010018944-A1 Blend including carbon black with given nitrogen adsorption specific surface area and 1,3-bis(citraconimidomethyl)benzene SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-09-06 US claimed
EP-1125976-A1 Chafer rubber composition, and heavy duty pneumatic tyre using the chafer rubber composition SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2001-08-22 EP claimed
US-5023339-A Blend with surfactant, protective colloid, and water NIPPON OIL AND FATS CO., LTD. (JP) 1991-06-11 US claimed