Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21825062 | 1.00 | DPP4 (0.48) | DPP4DPP9DPP8HSD11B1PRKAA2 | |
| SCHEMBL21886888 | 0.84 | GPR119 (0.58) | GPR119 | |
| SCHEMBL21887079 | 0.84 | GPR119 (0.58) | GPR119 | |
| SCHEMBL21886886 | 0.84 | GPR119 (0.58) | GPR119 | |
| SCHEMBL7105199 | 0.81 | MMP1 (0.47) | HSD11B1GPR119LIPGHMOX1 | |
| SCHEMBL16973134 | 0.81 | LIPG (0.43) | HSD11B1GPR119LIPGHMOX1 | |
| SCHEMBL596069 | 0.81 | LIPG (0.43) | HSD11B1GPR119LIPGHMOX1 | |
| SCHEMBL596068 | 0.81 | LIPG (0.43) | HSD11B1GPR119LIPGHMOX1 | |
| SCHEMBL20137537 | 0.81 | LIPE (0.45) | HSD11B1LIPGHMOX1HRH3 | |
| SCHEMBL18077130 | 0.81 | LIPE (0.45) | HSD11B1LIPGHMOX1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860992-A1 | NOVEL OXADIAZOLES | PI Industries Ltd. (IN) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |