SCHEMBL21829153

SCHEMBL21829153

C=CC(=O)Oc1ccc(C2(c3ccc(OC(=O)C=C)cc3)CCc3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.38
HDAC9 Q9UKV0 1/20 0.38
KIF11 P52732 2/20 0.35
HCAR2 Q8TDS4 1/20 0.34
HSD11B1 P28845 2/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
PDE6D O43924 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23524463 0.84 THRB (0.56) THRBHDAC9KIF11
SCHEMBL21829167 0.84 HDAC9 (0.36) HDAC9KIF11MAPTPOLB
SCHEMBL21829179 0.81 THRB (0.38) THRBKIF11MAPTPOLB
SCHEMBL28401840 0.81 CHRNA7 (0.38) THRBHDAC9KIF11MAPTPOLB
SCHEMBL29028353 0.79 CHRNA7 (0.37) THRBKIF11MAPTPOLB
SCHEMBL21976052 0.78 THRB (0.40) THRBKIF11MAPTPOLBPDE6D
SCHEMBL28329520 0.75 PIN1 (0.37) THRBHCAR2MAPT
SCHEMBL14701153 0.75 SIGMAR1 (0.50) KIF11MAPTPOLBSIGMAR1
SCHEMBL2777451 0.73 KDM1A (0.41) HDAC9MAPT
SCHEMBL811884 0.73 KMT2A (0.46) THRBMAPTPOLBPDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110392864-B Negative photosensitive resin composition, cured film, element and organic EL display having cured film, and method for producing same 东丽株式会社 2023-05-23 CN disclosed
US-11561470-B2 Negative photosensitive resin composition, cured film, element provided with cured film, organic EL display provided with cured film, and method for producing same TORAY INDUSTRIES, INC. (JP) 2023-01-24 US disclosed
US-20200110337-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT PROVIDED WITH CURED FILM, ORGANIC EL DISPLAY PROVIDED WITH CURED FILM, AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES, INC. (JP) 2020-04-09 US disclosed