Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834669 | 1.00 | MAPT (0.64) | MAPTALDH1A1LMNAKMT2AMCOLN2 | |
| SCHEMBL8752407 | 0.74 | LMNA (0.71) | MAPTALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL5058389 | 0.74 | L3MBTL1 (0.50) | MAPTALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL5063539 | 0.74 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL23355074 | 0.73 | MCOLN3 (0.70) | MAPTALDH1A1KMT2AMCOLN2MCOLN3 | |
| SCHEMBL9424048 | 0.73 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL29979154 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKMT2AMCOLN2 | |
| SCHEMBL23057150 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKMT2AMCOLN2 | |
| SCHEMBL21708292 | 0.72 | KEAP1 (0.60) | LMNAMCOLN3KEAP1NFE2L2 | |
| SCHEMBL8752442 | 0.72 | LMNA (0.71) | MAPTALDH1A1LMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067398-A1 | BIARYL SULFONAMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST CELL INVASION OF FILOVIRUS | 国立大学法人北海道大学 | 2020-04-02 | — | — | WO | disclosed |