Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242058 | 0.72 | CDK5 (0.57) | NPC1CDK5CDK5R1MAPTKDM4E | |
| SCHEMBL6249095 | 0.70 | RAB9A (0.50) | NPC1GBA1CDK5CDK5R1ALDH1A1 | |
| SCHEMBL6200227 | 0.69 | AR (0.52) | NPC1CDK5CDK5R1ALDH1A1MAPT | |
| SCHEMBL2226853 | 0.67 | LOXL2 (0.74) | HTR3ANPC1LOXL2TAAR1ALDH1A1 | |
| SCHEMBL5903189 | 0.67 | LMNA (0.50) | NPC1GBA1ALDH1A1MAPTKDM4E | |
| SCHEMBL4789520 | 0.67 | PDPK1 (0.58) | HTR3ACDK5CDK5R1 | |
| SCHEMBL2101505 | 0.67 | AURKA (0.56) | NPC1GBA1CDK5ALDH1A1MAPT | |
| SCHEMBL17873568 | 0.66 | AR (0.54) | NPC1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL28162272 | 0.65 | HRH3 (0.45) | NPC1GBA1TAAR1MAPTKMT2A | |
| SCHEMBL3919224 | 0.65 | TSHR (0.62) | NPC1LOXL2TAAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |