SCHEMBL2183544

SCHEMBL2183544

OB(O)c1cccc2[nH]c3ccccc3c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.58
IMPDH1 P20839 1/20 0.58
ALDH1A1 P00352 2/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.47
GABRP O00591 3/20 0.47
GABRD O14764 3/20 0.47
GABRA1 P14867 3/20 0.47
GABRB1 P18505 3/20 0.47
GABRG2 P18507 3/20 0.47
GABRB3 P28472 3/20 0.47
GABRA5 P31644 3/20 0.47
GABRA3 P34903 3/20 0.47
GABRA2 P47869 3/20 0.47
GABRB2 P47870 3/20 0.47
GABRA4 P48169 3/20 0.47
GABRE P78334 3/20 0.47
GABRA6 Q16445 3/20 0.47
GABRG1 Q8N1C3 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954176 1.00 IMPDH2 (0.58) IMPDH2IMPDH1ALDH1A1GPR3HSD17B10
SCHEMBL6114238 0.86 IMPDH2 (0.51) IMPDH2IMPDH1ALDH1A1GPR3HSD17B10
SCHEMBL12411332 0.80 IMPDH2 (0.49) IMPDH2IMPDH1ALDH1A1GPR3HSD17B10
SCHEMBL19988526 0.79 KDM4E (0.47) IMPDH2IMPDH1ALDH1A1GPR3HSD17B10
SCHEMBL31287344 0.77 KIF11 (0.58) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL29792060 0.77 KIF11 (0.58) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL13388204 0.77 KIF11 (0.58) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL31419513 0.74 ALDH1A1 (0.44) ALDH1A1HSD17B10MAPTHPGD
SCHEMBL19667863 0.74 ALDH1A1 (0.44) ALDH1A1HSD17B10MAPTHPGD
SCHEMBL14740732 0.74 IMPDH2 (0.50) IMPDH2IMPDH1ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12209083-B2 Polycyclic compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2025-01-28 US disclosed
CN-113666913-B Organic compound and application thereof in organic light-emitting field 北京鼎材科技有限公司 2024-09-06 CN disclosed
CN-112105615-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2024-03-26 CN disclosed
WO-2023204529-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME (주)피엔에이치테크 2023-10-26 WO disclosed
CN-114230573-A Compound and application thereof 北京鼎材科技有限公司 2022-03-25 CN disclosed
CN-113666913-A Organic compound and application thereof in organic light-emitting field 北京鼎材科技有限公司 2021-11-19 CN disclosed
CN-113248477-A Organic compound, organic electroluminescent material and organic electroluminescent element 北京八亿时空液晶科技股份有限公司 2021-08-13 CN disclosed
CN-109659448-B Organic mixture, composition and organic electronic device 广州华睿光电材料有限公司 2021-07-06 CN disclosed
US-20210078992-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-03-18 US disclosed
US-20210078992-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-03-18 US disclosed
WO-2020009492-A9 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-12-30 WO disclosed
CN-112105615-A Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2020-12-18 CN disclosed
WO-2020228359-A1 ORGANIC LIGHT-EMITTING MATERIAL CONTAINING TETRAPHENYLBENZENE, PREPARATION, AND APPLICATION 华南理工大学 2020-11-19 WO disclosed
US-8309721-B2 HSP90 inhibitory carbazole derivatives, compositions containing same and use thereof SANOFI (FR) 2012-11-13 US disclosed
US-20110166169-A1 NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF SANOFI-AVENTIS (FR) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210078992-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME CRY1, ODC1, PPOX IMPDH2 1410/4885IMPDH1 837/4885ALDH1A1 14/4885
US-20110166169-A1 NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF HSP90AB2P, HSP90AB1, HSP90AA1 IMPDH2 3926/4885IMPDH1 4250/4885ALDH1A1 1673/4885
US-12209083-B2 Polycyclic compound and organic light emitting diode comprising same CRY1, ODC1, PPOX IMPDH2 1410/4885IMPDH1 837/4885ALDH1A1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.