SCHEMBL218360

SCHEMBL218360

COc1cccc2c1[CH]c1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ALDH1A1 P00352 6/20 0.43
TDP1 Q9NUW8 2/20 0.43
ADRA2B P18089 1/20 0.43
PTGS1 P23219 1/20 0.43
APP P05067 1/20 0.42
PTGS2 P35354 1/20 0.42
TOP1 P11387 1/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 1/20 0.39
DCUN1D1 Q96GG9 1/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217122 0.81 ALDH1A1 (0.32) ALDH1A1PTGS2DCUN1D1HPGDSMN1; SMN2
SCHEMBL4921197 0.79 ALDH1A1 (0.48) ALDH1A1TDP1MAPTKDM4EHPGD
SCHEMBL218366 0.79 RAB9A (0.47) CA1CA2CA7CA9CA12
SCHEMBL328869 0.77 NCOA1 (0.40) ALDH1A1PTGS2TSHRKMT2AHPGD
SCHEMBL4916059 0.77 CYP1A2 (0.42) ALDH1A1TP53TSHRMAPTKDM4E
SCHEMBL7525316 0.76 CA1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL4915520 0.75 CYP1A2 (0.53) MAPTKDM4EMEN1KMT2ALMNA
SCHEMBL4723230 0.75 ALDH1A1 (0.43) ALDH1A1TDP1PTGS2TP53MAPT
SCHEMBL4721475 0.74 MAPT (0.50) ALDH1A1TDP1MAPTKDM4EMEN1
SCHEMBL6891983 0.74 GPR84 (0.45) ALDH1A1APPPTGS2HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296738-B2 Organic electroluminescent material, the process for preparing the same and OLED device using the same EVERDISPLAY OPTRONICS (SHANGHAI) LIMITED (CN) 2016-03-29 US claimed
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME EVERDISPLAY OPTRONICS (SHANGHAI) CO., LTD. (CN) 2015-07-23 US claimed
EP-3438102-B1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD KOLON INC (KR) 2021-07-07 EP disclosed
US-10954206-B2 Glycidyl ester compound preparation method KOLON INDUSTRIES, INC. (KR) 2021-03-23 US disclosed
US-20200299247-A1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD KOLON INDUSTRIES, INC. (KR) 2020-09-24 US disclosed
EP-3495424-B1 COMPOSITION FOR PHOTO-ALIGNMENT LAYER AND PHOTO-ALIGNMENT LAYER LG CHEMICAL LTD (KR) 2020-09-09 EP disclosed
CN-107109231-B Vertically oriented layer comprising cyclic olefin (co) polymer 株式会社LG化学 2020-03-06 CN disclosed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US disclosed
EP-3495424-A1 COMPOSITION FOR PHOTO-ALIGNMENT LAYER AND PHOTO-ALIGNMENT LAYER LG Chem, Ltd. (KR) 2019-06-12 EP disclosed
EP-3196236-B1 VERTICAL ALIGNMENT FILM COMPRISING (CO)POLYMER OF CYCLIC OLEFIN COMPOUND LG CHEMICAL LTD (KR) 2019-04-10 EP disclosed
US-20190079060-A1 Pretreatment Method For Analyzing Dioxin Compounds And Analytical Method Using The Same LG CHEM, LTD. (KR) 2019-03-14 US disclosed
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PFIZER INC. 2008-08-21 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
EP-1866317-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2007-12-19 EP disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
WO-2006103555-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
US-5688735-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 1997-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME OCIAD1, OCIAD2, OR10J3 CA1 3607/4885CA2 3257/4885CA7 4138/4885
US-20200299247-A1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD AGER, CYP4A11, GK CA1 3545/4885CA2 3144/4885CA7 641/4885
US-10954206-B2 Glycidyl ester compound preparation method AGER, CYP4A11, GK CA1 3545/4885CA2 3144/4885CA7 641/4885
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PF4, TBXA2R, P2RY4 CA1 4557/4885CA2 2288/4885CA7 4121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.