Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320389 | 1.00 | CYP2C19 (0.54) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL7317737 | 0.97 | CYP2C19 (0.50) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL15919215 | 0.87 | — | — | |
| SCHEMBL2192649 | 0.76 | CYP2C19 (0.35) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL3421776 | 0.74 | ALDH1A1 (0.74) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL98282 | 0.74 | ALDH1A1 (0.74) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| Cyclohexane SCHEMBL9536108 | 0.74 | CYP2C19 (0.58) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL3345554 | 0.74 | CYP2C19 (0.58) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL2871721 | 0.74 | ALDH1A1 (0.74) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL10602483 | 0.74 | ALDH1A1 (0.74) | CYP2C19ALDH1A1CYP1A2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438925-A2 | Compounds that modulate neuronal growth and their uses | Wyeth LLC (US) | 2012-04-11 | — | — | EP | claimed |
| EP-0937103-B1 | COMPOUNDS AND METHODS FOR MODULATING CELL ADHESION | UNIV MCGILL (CA) | 2007-11-28 | — | — | EP | claimed |
| EP-1042365-B1 | COMPOUNDS AND METHODS FOR MODULATING OCCLUDIN RELATED TISSUE PERMEABILITY | ADHEREX TECHNOLOGIES INC (CA) | 2007-07-25 | — | — | EP | claimed |
| US-7138369-B2 | Compounds and methods for modulating apoptosis | MCGILL UNIVERSITY (CA) | 2006-11-21 | — | — | US | claimed |
| US-20060183884-A1 | Compounds and methods for modulating cell adhesion | ADHEREX TECHNOLOGIES, INC. (CA) | 2006-08-17 | — | — | US | claimed |
| US-20050164920-A1 | Compounds that modulate neuronal growth and their uses | WYETH (US) | 2005-07-28 | — | — | US | claimed |
| US-6914044-B2 | Compounds and methods for modulating cell adhesion | MCGILL UNIVERSITY (CA) | 2005-07-05 | — | — | US | claimed |
| US-20040106545-A1 | Compounds and methods for modulating cell adhesion | ADHEREX TECHNOLOGIES INC. (CA) | 2004-06-03 | — | — | US | claimed |
| US-20030224978-A1 | Compounds and methods for modulating apoptosis | MCGILL UNIVERSITY (CA) | 2003-12-04 | — | — | US | claimed |
| US-6610821-B1 | Cyclic peptide of given amino acid sequence; can use to improve drug delivery process, inhibit angiogenesis, increase vasopermeability; treatment of autoimmune and inflammatory diseases | MCGILL UNIVERSITY (CA) | 2003-08-26 | — | — | US | claimed |
| US-6031072-A | CYCLIC PEPTIDE WHICH MODULATES CADHERIN-MEDIATED PROCESSES; COMPRISING THE SEQUENCE HIS-ALA-VAL WITHIN A CYCLIC PEPTIDE RING THAT CONTAINS 4-15 AMINO ACIDS; FOR IMPROVED DRUG DELIVERY; ANTIMETASTASIS AGENTS | MCGILL UNIVERSITY (CA) | 2000-02-29 | — | — | US | claimed |
| US-5955572-A | CYCLIC PEPTIDES THAT MIMIC THE ARGININE-GLYCINE-ASPARTIC ACID BINDING SITE OF INTEGRINS; FOR MODULATING THE CELL AGGREGATION AND CELL ADHESION; THROMBOLYTIC/ANTIINFLAMMATORY AGENTS; ANTIMETASTASIS/WOUND HEALING AGENTS | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1999-09-21 | — | — | US | claimed |
| WO-1999033875-A1 | COMPOUNDS AND METHODS FOR MODULATING SYNAPTIC STABILITY | MCGILL UNIVERSITY (CA) | 1999-07-08 | — | — | WO | claimed |
| US-5817750-A | INTEGRINS, INHIBITING CELL ADHESION | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1998-10-06 | — | — | US | claimed |
| WO-1997008203-A1 | STRUCTURAL MIMICS OF RGD-BINDING SITES | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1997-03-06 | — | — | WO | claimed |
| EP-0537291-A4 | METHOD OF TREATING NAUSEA AND EMESIS RELATED TO MOTION SICKNESS | — | 1993-07-28 | — | — | EP | claimed |
| EP-0537291-A1 | METHOD OF TREATING NAUSEA AND EMESIS RELATED TO MOTION SICKNESS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-21 | — | — | EP | claimed |
| WO-1992000094-A1 | METHOD OF TREATING NAUSEA AND EMESIS RELATED TO MOTION SICKNESS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-09 | — | — | WO | claimed |
| US-4684716-A | VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-04 | — | — | US | claimed |
| EP-0189326-A2 | Derivatives of arginine vasopressin antagonists | Medical College of Ohio (US) | 1986-07-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106545-A1 | Compounds and methods for modulating cell adhesion | CDH1, EPCAM, VCAM1 | CYP2C19 4875/4885ALDH1A1 3559/4885CYP1A2 4884/4885 |
| US-20030224978-A1 | Compounds and methods for modulating apoptosis | CDH1, BAX, BAD | CYP2C19 4877/4885ALDH1A1 4367/4885CYP1A2 4885/4885 |
| US-20060183884-A1 | Compounds and methods for modulating cell adhesion | CDH1, EPCAM, VCAM1 | CYP2C19 4875/4885ALDH1A1 3559/4885CYP1A2 4884/4885 |
| US-20050164920-A1 | Compounds that modulate neuronal growth and their uses | NTRK2, BDNF, NGF | CYP2C19 4875/4885ALDH1A1 4321/4885CYP1A2 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.