Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.40 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.40 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696292 | 0.83 | PTGER4 (0.46) | — | |
| SCHEMBL29388202 | 0.82 | PREP (0.51) | FAPPREP | |
| SCHEMBL6274793 | 0.81 | FAP (0.49) | FAPF10PRSS1PLGPREP | |
| SCHEMBL4301229 | 0.81 | PTGER4 (0.44) | — | |
| SCHEMBL22209369 | 0.80 | MALT1 (0.50) | FAPF10PRSS1PREP | |
| SCHEMBL5053920 | 0.80 | PSMB1 (0.47) | — | |
| SCHEMBL18873440 | 0.80 | PREP (0.45) | FAPNTMT1PREP | |
| Hydrochloric Acid SCHEMBL18831927 | 0.79 | PREP (0.44) | FAPNTMT1PREP | |
| Hydrochloric Acid SCHEMBL18831929 | 0.79 | PREP (0.44) | FAPNTMT1PREP | |
| SCHEMBL31437669 | 0.78 | NTMT1 (0.50) | NTMT1NMUR2NMUR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593138-B2 | Nitrile-containing enzyme inhibitors and ruthenium complexes thereof | WAYNE STATE UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| EP-2344662-B1 | REACTION MEDIUM FOR METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) BACTERIA | BIOMERIEUX SA (FR) | 2016-12-07 | — | — | EP | disclosed |
| US-20140100173-A1 | Nitrile-containing enzyme inhibitors and ruthenium complexes thereof | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-04-10 | — | — | US | disclosed |
| US-8415115-B2 | Reaction medium for methicillin-resistant Staphylococcus aureus (MRSA) bacteria | BIOMERIEUX (FR) | 2013-04-09 | — | — | US | disclosed |
| US-20110165604-A1 | REACTION MEDIUM FOR METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) BACTERIA | BIOMERIEUX (FR) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140100173-A1 | Nitrile-containing enzyme inhibitors and ruthenium complexes thereof | SERPINB1, CTRL, RNASE1 | FAP 57/4885F10 1168/4885PRSS1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.