SCHEMBL218448

SCHEMBL218448

CC1=C(C)c2c(C)cccc2[CH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.36
CYP1A2 P05177 1/20 0.36
CD44 P16070 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
TSHR P16473 1/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 2/20 0.35
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
DPP4 P27487 2/20 0.32
MYC P01106 1/20 0.31
TRPA1 O75762 2/20 0.31
ATM Q13315 2/20 0.31
ANPEP P15144 1/20 0.31
SCN4A P35499 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2050326 0.79 CD44 (0.48) CYP2A6CYP1A2CD44CA1CA2
SCHEMBL2965002 0.77 PBRM1 (0.36) CYP2A6CYP1A2TSHRALDH1A1GRIA1
SCHEMBL2962654 0.77 ALDH1A1 (0.36) CA1CA2CA7CA9ALDH1A1
SCHEMBL7032912 0.76 TAAR1 (0.33) CYP2A6CYP1A2CD44CA1CA2
SCHEMBL3154185 0.74 ELANE (0.33) CYP2A6CYP1A2CD44CA1CA2
SCHEMBL2966629 0.73 ADORA3 (0.35) CYP2A6CYP1A2CD44CA1CA2
SCHEMBL5691260 0.73 ADORA3 (0.38) TSHRALDH1A1MEN1KMT2A
SCHEMBL2964933 0.73 FABP4 (0.35) CYP2A6TSHRACHECYP3A4TDP1
SCHEMBL5600529 0.73 PDCD1 (0.39) CYP2A6CA2CA9ALDH1A1
SCHEMBL2044930 0.71 TDP2 (0.43) HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363955-B1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORP (KR) 2008-04-09 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-6943225-B2 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2005-09-13 US claimed
WO-2004076502-A1 SUPPORTED MULTINUCLEAR METALLOCENE CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PREPARING THE SAME HONAM PETROCHEMICAL CORPORATION (KR) 2004-09-10 WO claimed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US claimed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP claimed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO claimed
WO-2020204188-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER ポリプラスチックス株式会社 2020-10-08 WO disclosed
WO-2020071494-A1 METHOD FOR PRODUCING CYCLIC OLEFIN POLYMER ポリプラスチックス株式会社 2020-04-09 WO disclosed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
EP-0543022-A1 PROCESS FOR PRODUCING STYRENIC POLYMER AND CATALYST THEREFOR IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-05-26 EP disclosed
EP-0535582-A1 Process for producing styrenic polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-04-07 EP disclosed
EP-0505890-A2 Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505973-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0497207-A2 Process for purification of styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-08-05 EP disclosed
EP-0492282-A1 Process for producing a styrene polymer and a catalyst for use therein IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-01 EP disclosed