Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083972 | 0.85 | NPC1 (0.52) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL19156951 | 0.81 | NPC1 (0.52) | RAB9ANPC1KMT2AMEN1TP53 | |
| SCHEMBL20083976 | 0.79 | ACKR3 (0.49) | PARP1KMT2AMEN1POLBHTR1A | |
| SCHEMBL19157226 | 0.79 | HTR1A (0.41) | PARP1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15276842 | 0.78 | KMT2A (0.60) | RAB9ANPC1KMT2AMEN1CNR1 | |
| SCHEMBL21844836 | 0.78 | ACKR3 (0.51) | PARP1KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL21844943 | 0.77 | ALDH1A1 (0.54) | RAB9AKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL21844945 | 0.77 | ACKR3 (0.53) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL21844913 | 0.76 | MCHR1 (0.48) | RAB9ANPC1KMT2AMEN1CNR1 | |
| SCHEMBL21844832 | 0.74 | ACKR3 (0.50) | RAB9ANPC1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |