Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455495 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL2137537 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3128648 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9235251 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL625642 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL2137541 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3625233 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL2184557 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3625235 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3623659 | 1.00 | FAAH (0.58) | FAAHTRPV1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189622-B1 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GENZYME CORP (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1800687-A2 | Anionic polymers as toxin binders and antibacterial agents | GENZYME CORPORATION (US) | 2007-06-27 | — | — | EP | claimed |
| EP-0915705-B1 | IONIC POLYMERS AS ANTI-INFECTIVE AGENTS | GENZYME CORP (US) | 2007-01-10 | — | — | EP | claimed |
| US-6890523-B2 | Anionic polymers as toxin binders and antibacterial agents | GENZYME CORPORATION (US) | 2005-05-10 | — | — | US | claimed |
| EP-1014999-B1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GENZYME CORP (US) | 2004-12-08 | — | — | EP | claimed |
| US-20030138397-A1 | Anionic polymers as toxin binders and antibacterial agents | GELTEX PHARMACEUTICALS, INC. | 2003-07-24 | — | — | US | claimed |
| US-6593366-B2 | Cationic quaternery ammonium containing polymers for treatment of gastrointestinal disorders; cytotoxicity | GELTEX PHARMACEUTICALS, INC. | 2003-07-15 | — | — | US | claimed |
| JP-2002544226-A | — | — | 2002-12-24 | — | — | JP | claimed |
| US-20020114777-A1 | Ionic polymers as anti-infective agents | GELTEX PHARMACEUTICALS, INC. (US) | 2002-08-22 | — | — | US | claimed |
| US-6395777-B2 | ORGANONITROGEN POLYMERS | GELTEX PHARMACEUTICALS, INC. | 2002-05-28 | — | — | US | claimed |
| EP-1189622-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | Geltex Pharmaceuticals, Inc. (US) | 2002-03-27 | — | — | EP | claimed |
| US-20010053794-A1 | Ionic polymers as anti-infective agents | GENZYME CORPORATION | 2001-12-20 | — | — | US | claimed |
| US-20010041171-A1 | Anionic polymers as toxin binders | GELTEX PHARMACEUTICALS, INC. (US) | 2001-11-15 | — | — | US | claimed |
| US-6270755-B1 | POLYMER COMPRISING PENDANT ACID FUNCTIONAL GROUPS OR A SALT THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE CATION, SAID POLYMER COMPRISING NO ACID ANHYDRIDE GROUPS. | GELTEX PHARMACEUTICALS, INC. | 2001-08-07 | — | — | US | claimed |
| WO-2000069428-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 2000-11-23 | — | — | WO | claimed |
| EP-1014999-A1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 2000-07-05 | — | — | EP | claimed |
| US-6007803-A | ADMINISTERING TO MAMMAL A CATIONIC POLYMER TO INHIBIT PATHOGENIC TOXINS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-12-28 | — | — | US | claimed |
| EP-0915705-A1 | IONIC POLYMERS AS ANTI-INFECTIVE AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-05-19 | — | — | EP | claimed |
| WO-1999015186-A1 | CATIONIC POLYMERS AS TOXIN-BINDING AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-04-01 | — | — | WO | claimed |
| WO-1997049413-A1 | IONIC POLYMERS AS ANTI-INFECTIVE AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 1997-12-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041171-A1 | Anionic polymers as toxin binders | PIGS, CD47, BTD | FAAH 1749/4885TRPV1 2528/4885CYP1A2 4873/4885 |
| US-20010053794-A1 | Ionic polymers as anti-infective agents | PAM, ARG1, PIGS | FAAH 2440/4885TRPV1 910/4885CYP1A2 4823/4885 |
| US-20020114777-A1 | Ionic polymers as anti-infective agents | PAM, ARG1, PIGS | FAAH 2440/4885TRPV1 910/4885CYP1A2 4823/4885 |
| US-20030138397-A1 | Anionic polymers as toxin binders and antibacterial agents | MSN, ANTXR2, PNKP | FAAH 2469/4885TRPV1 2841/4885CYP1A2 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.