SCHEMBL2184599

SCHEMBL2184599

CCCCCCCCCCCCOP(OCCCCCCCCCCCC)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.36
▸ ALDH1A1 P00352 5/20 0.33
▸ THRA P10827 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ NR5A1 Q13285 1/20 0.33
▸ RXRA P19793 1/20 0.32
▸ RXRB P28702 1/20 0.32
▸ RXRG P48443 1/20 0.32
▸ LTA4H P09960 1/20 0.32
▸ GABRA1 P14867 1/20 0.32
▸ GABRB2 P47870 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ GGPS1 O95749 1/20 0.32
▸ MCHR1 Q99705 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17709416 0.97 TSHR (0.36) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL8392146 0.92 TSHR (0.33) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL8392142 0.85 TSHR (0.34) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL22323559 0.84 ALDH1A1 (0.44) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL11137750 0.83 ALDH1A1 (0.36) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL11428133 0.81 ALDH1A1 (0.44) TSHRALDH1A1THRATHRBKDM4E
SCHEMBL10816208 0.79 HSPA5 (0.36) THRATHRBNR5A1
SCHEMBL75583 0.76 CA2 (0.46) TSHRALDH1A1KDM4EGABRA1GABRB2
SCHEMBL11213999 0.74 THRA (0.40) THRATHRBKDM4EGAA
SCHEMBL11216723 0.74 THRB (0.40) ALDH1A1THRATHRBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111337-B Process for preparing halogenated polymers 阿科玛法国公司 2021-05-07 — — CN disclosed
EP-2807197-B1 METHOD FOR PREPARING HALOGENATED POLYMERS ARKEMA FRANCE (FR) 2021-04-28 — — EP disclosed
EP-3498720-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC Organometallix, Inc. (US) 2019-06-19 — — EP disclosed
EP-2300487-B1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC ORGANOMETALLIX INC (US) 2019-03-13 — — EP disclosed
EP-3030610-B1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS GALATA CHEMICALS LLC (US) 2017-05-17 — — EP disclosed
US-9587088-B2 Heat stabilizer for halogen-containing polymers GALATA CHEMICALS LLC (US) 2017-03-07 — — US disclosed
US-20160194478-A1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS CITIZENS BANK, N.A. 2016-07-07 — — US disclosed
EP-3030610-A1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS Galata Chemicals LLC (US) 2016-06-15 — — EP disclosed
US-9346939-B2 Flexible PVC compounds having a low metals content GALATA CHEMICALS LLC (US) 2016-05-24 — — US disclosed
US-9221933-B2 Process for preparing halogenated polymers ARKEMA FRANCE (FR) 2015-12-29 — — US disclosed
EP-0224438-B1 ALPHA-BETA-UNSATURATED CARBONYL COMPOUNDS CIBA-GEIGY AG (CH) 1989-04-05 — — EP disclosed
US-4786672-A STABILIZATION OF POLYVINYL CHLORIDE CIBA-GEIGY CORPORATION (US) 1988-11-22 — — US disclosed
US-4743640-A HEAT AND LIGHT RESISTANCE CIBA-GEIGY CORPORATION (US) 1988-05-10 — — US disclosed
EP-0260226-A2 Stabilized chlorine-containing polymers CIBA-GEIGY AG (CH) 1988-03-16 — — EP disclosed
EP-0255801-A2 Anilinotriazines and their use CIBA-GEIGY AG (CH) 1988-02-10 — — EP disclosed
EP-0224438-A1 Alpha-beta-unsaturated carbonyl compounds CIBA-GEIGY AG (CH) 1987-06-03 — — EP disclosed
US-4656209-A VINYL CHLORIDE POLYMERS PROTECTED AGAINST HEAT INDUCED DEGRADATION CIBA-GEIGY CORPORATION (US) 1987-04-07 — — US disclosed
US-4642322-A Stabilization of chlorine-containing thermoplastics with nitrogen-containing organic compounds CIBA-GEIGY CORPORATION (US) 1987-02-10 — — US disclosed
US-4385147-A Stabilization of chlorine-containing thermoplastics with m-aminophenol derivatives CIBA-GEIGY CORPORATION (US) 1983-05-24 — — US disclosed
US-4369276-A Pyrrole stabilizers for chlorine-containing thermoplastics CIBA-GEIGY CORPORATION (US) 1983-01-18 — — US disclosed
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