SCHEMBL2184723

SCHEMBL2184723

C=C(C)C(=O)OC(Oc1ccc(C(C)(C)C)cc1)C(C)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 3/20 0.43
MAPT P10636 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
ALOX15 P16050 1/20 0.38
APEX1 P27695 1/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
EPHX2 P34913 2/20 0.36
TRPV1 Q8NER1 2/20 0.36
MEN1 O00255 2/20 0.36
NPC1 O15118 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5922597 0.93 AR (0.36) NR1H4TDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL2170374 0.86 HMGCR (0.31) NR1H4
SCHEMBL2859020 0.82 MTNR1A (0.42) MAPTTDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL4904406 0.80 ESR1 (0.36) TDP1ALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL59814 0.77 AR (0.39) NR1H4MAPTTDP1ALDH1A1HSD17B10
SCHEMBL2181924 0.75 TSHR (0.33) MAPTTDP1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL11341219 0.75 LMNA (0.46) TDP1ALDH1A1LMNARECQLSMN1; SMN2
SCHEMBL33915 0.74 ELANE (0.56) MAPTTDP1ALDH1A1LMNAALOX15
SCHEMBL6904850 0.73 AR (0.36) NR1H4MAPTTDP1ALDH1A1SMN1; SMN2
Propane SCHEMBL9476269 0.73 AR (0.39) NR1H4TDP1ALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346910-B1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI DENTAL DIVISION (US) 2016-07-13 EP disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
CN-102405241-A Carbamate-methylpropionate monomers and their use in dental applications SEPTODONT CONFI DENTAL DIVISIO 2012-04-04 CN disclosed
EP-2346910-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS Septodont Confi-Dental Division (US) 2011-07-27 EP disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 US disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB NR1H4 4695/4885MAPT 775/4885TDP1 1282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.