SCHEMBL2170374

SCHEMBL2170374

C=C(C)C(=O)OC(Oc1cc(C(C)(C)C)cc(C(C)(C)C)c1)C(C)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.31
NR1H4 Q96RI1 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184723 0.86 NR1H4 (0.43) NR1H4
SCHEMBL4904406 0.83 ESR1 (0.36)
SCHEMBL5922597 0.82 AR (0.36) NR1H4
SCHEMBL2181924 0.81 TSHR (0.33)
SCHEMBL2859020 0.77 MTNR1A (0.42)
SCHEMBL11341219 0.75 LMNA (0.46)
SCHEMBL28252558 0.73 RXRA (0.47) GABRA1
SCHEMBL649529 0.73 TSHR (0.45)
SCHEMBL11477473 0.69 TSHR (0.42)
SCHEMBL2170378 0.69 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346910-B1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI DENTAL DIVISION (US) 2016-07-13 EP disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
EP-2346910-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS Septodont Confi-Dental Division (US) 2011-07-27 EP disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 US disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB HMGCR 4031/4885NR1H4 4695/4885GABRA1 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.