Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184106 | 0.85 | ALDH1A1 (0.44) | NPSR1TRIM24TRIM33UNGCYP19A1 | |
| SCHEMBL8669208 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2CA1CA2 | |
| SCHEMBL2183782 | 0.78 | NPSR1 (0.53) | NPSR1TRIM24TRIM33UNGCYP19A1 | |
| SCHEMBL2183578 | 0.78 | CYP19A1 (0.43) | NPSR1CYP19A1MAOAMAOBALDH1A1 | |
| SCHEMBL8670587 | 0.77 | CYP19A1 (0.48) | NPSR1CYP19A1MAOAMAOBALDH1A1 | |
| Terephthalic Acid SCHEMBL8011410 | 0.76 | TSHR (0.57) | NPSR1PBRM1RXRARXRBTSHR | |
| SCHEMBL8668550 | 0.74 | UNG (0.62) | UNGANPEPENPEP | |
| Aminomethylbenzoic Acid SCHEMBL4654815 | 0.74 | PBRM1 (0.53) | ALDH1A1PBRM1TSHRCA1CA2 | |
| SCHEMBL6866238 | 0.74 | PLA2G2A (0.53) | CYP19A1MAOAMAOBALDH1A1BCL2 | |
| SCHEMBL2185169 | 0.71 | RXRA (0.53) | ALDH1A1RXRARXRBTSHRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110165700-A1 | CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS | ALCHEMIA LIMITED (AU) | 2011-07-07 | — | — | US | claimed |
| US-20080176936-A1 | Classes of Compounds that Interact with Integrins | ALCHEMIA LIMITED (AU) | 2008-07-24 | — | — | US | claimed |
| US-20110165700-A1 | CLASSES OF COMPOUNDS THAT INTERACT WITH INTEGRINS | ALCHEMIA LIMITED (AU) | 2011-07-07 | — | — | US | disclosed |
| US-20080176936-A1 | Classes of Compounds that Interact with Integrins | ALCHEMIA LIMITED (AU) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176936-A1 | Classes of Compounds that Interact with Integrins | ITGB3, ITGB5, ITGA5 | NPSR1 91/4885TRIM24 1957/4885TRIM33 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.