Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27949936 | 0.98 | CNR2 (0.35) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL27890396 | 0.80 | CNR2 (0.36) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL27948460 | 0.80 | HTR1A (0.39) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL27932933 | 0.80 | CNR2 (0.39) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL2355308 | 0.80 | MAPT (0.36) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL5948340 | 0.78 | CNR2 (0.35) | CNR2MAPTGAAHTR1ATDP1 | |
| SCHEMBL30729387 | 0.73 | CHEK1 (0.37) | CNR2SMN1; SMN2DRD4 | |
| SCHEMBL22169108 | 0.73 | CNR2 (0.37) | CNR2MAPTGAATDP1CYP2C9 | |
| SCHEMBL29947345 | 0.73 | DRD4 (0.35) | CNR2CYP2C9DRD4CYP1A2 | |
| SCHEMBL657883 | 0.72 | MAPT (0.50) | MAPTGAACYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483431-A | Linezolid impurity compound, preparation method and its application | GUILIN PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-110194750-A | A kind of preparation method and refining methd of Linezolid | 四川美大康华康药业有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-109232457-A | A kind of preparation method of Linezolid | 华夏生生药业(北京)有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-105348212-B | The preparation method of Linezolid | 安徽悦康凯悦制药有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-108640888-A | A kind of double fluoro- 4- morpholinyl phenylamines schiff bases of halogenated salicylaldehyde contracting 3- and its preparation method and application | 淮阴师范学院 | 2018-10-12 | — | — | CN | claimed |
| CN-108339551-A | A kind of preparation method of novel antibacterial medicine linezolid intermediate | 邵宏超 | 2018-07-31 | — | — | CN | claimed |
| CN-106316988-B | The preparation method of Linezolid Injection degradation impurity | 重庆常捷医药有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-108191793-A | Fluoro- 4- morpholinyl phenylamines schiff bases of new compound salicylidene 3- and its preparation method and application | 淮阴师范学院 | 2018-06-22 | — | — | CN | claimed |
| CN-107540625-A | A kind of preparation method of Linezolid | 正大天晴药业集团股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-103420933-B | A kind of preparation method of Linezolid | LUNAN PHARMACEUTICAL GROUP CO., LTD. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104672217-A | New linezolid intermediate, preparation method thereof, and linezolid synthesis method | BEIJING ZHONGHE MINJIAN PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-102351807-B | Dibenzyl-1,3-oxazolidine-2-ketone compound and preparation method and application thereof | UNIV SICHUAN | 2015-04-29 | — | — | CN | claimed |
| CN-104529944-A | Synthesis process of linezolid intermediate | GANSU PUAN PHARMACEUTICAL LTD | 2015-04-22 | — | — | CN | claimed |
| CN-102977056-B | Synthesis method of N-carbobenzoxy-3-fluoro-4-morpholinylaniline | SHENZHEN MAIN LUCK PHARMACEUTICALS INC | 2014-11-26 | — | — | CN | claimed |
| CN-102558085-B | Method for preparing inezolid | FANGSHENG PHARMACEUTICAL | 2014-07-02 | — | — | CN | claimed |
| CN-102731336-B | Linezolid intermediate and synthetic method of linezolid | ZHEJIANG MED XINCHANG PHARM | 2014-05-07 | — | — | CN | claimed |
| CN-103724295-A | Method for preparing linezolid intermediate | CHENGDU YILUKANG MEDICAL TECHNOLOGY & SERVICE CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-103664813-A | Preparation method of linezolid | SHENYANG J & HEALTH PHARAMACEUTICAL CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103420933-A | Linezolid preparation method | LUNAN PHARM GROUP CORP | 2013-12-04 | — | — | CN | claimed |
| CN-103391927-A | Novel preparation method of linezolid and novel intermediate thereof | LEE PHARMA LTD | 2013-11-13 | — | — | CN | claimed |