Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK7 | P50613 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947345 | 0.78 | DRD4 (0.35) | CNR2HRH3DRD4 | |
| SCHEMBL27948460 | 0.76 | HTR1A (0.39) | PIM1GSK3AGSK3BPRKCQAAK1 | |
| SCHEMBL18436051 | 0.75 | LMNA (0.43) | CHEK1PIM1PRKACACLK2GSK3A | |
| SCHEMBL5948340 | 0.74 | CNR2 (0.35) | CNR2HRH3DRD4SIGMAR1 | |
| SCHEMBL7924048 | 0.73 | DRD4 (0.66) | DRD4 | |
| SCHEMBL2355308 | 0.73 | MAPT (0.36) | CNR2SMN1; SMN2 | |
| SCHEMBL21848255 | 0.73 | CNR2 (0.36) | CNR2DRD4SMN1; SMN2 | |
| SCHEMBL27932933 | 0.73 | CNR2 (0.39) | CNR2DRD4SMN1; SMN2 | |
| SCHEMBL27890396 | 0.73 | CNR2 (0.36) | CNR2DRD4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10513895 | 0.72 | DRD4 (0.64) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377673-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-01-09 | — | — | CN | disclosed |