Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21849219 | 0.84 | L3MBTL1 (0.56) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL16216287 | 0.81 | KDM4E (0.54) | LMNAPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13567551 | 0.81 | KDM4E (0.54) | LMNAPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18764220 | 0.77 | L3MBTL1 (0.45) | L3MBTL1LMNAPOLBHTTKDM4E | |
| SCHEMBL19155927 | 0.76 | L3MBTL1 (0.47) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL12384897 | 0.75 | L3MBTL1 (0.56) | L3MBTL1LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL21325321 | 0.74 | L3MBTL1 (0.40) | L3MBTL1LMNAPOLBHTTSOD1 | |
| SCHEMBL25948414 | 0.74 | CNR1 (0.39) | L3MBTL1LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL10458221 | 0.73 | L3MBTL1 (0.60) | L3MBTL1LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL10705548 | 0.72 | CHRNB2 (0.57) | LMNAPOLBSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | L3MBTL1 1131/4885LMNA 1845/4885POLB 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.