Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849704 | 0.87 | CYP1A2 (0.40) | CYP1A2CYP2A6ALDH1A1ELANESMN1; SMN2 | |
| SCHEMBL29440644 | 0.78 | MAOA (0.58) | MAOAMAOBCYP1A2CYP2A6MAPT | |
| SCHEMBL147819 | 0.78 | MAOA (0.58) | MAOAMAOBCYP1A2CYP2A6MAPT | |
| SCHEMBL23527389 | 0.77 | TSHR (0.41) | CYP1A2CYP2A6MAPTALDH1A1TP53 | |
| SCHEMBL17914397 | 0.75 | ATM (0.33) | CYP1A2ALDH1A1TDP1KIF11TSHR | |
| SCHEMBL21850735 | 0.75 | POLB (0.32) | CYP1A2ALDH1A1POLBTDP1KIF11 | |
| SCHEMBL12251301 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2A6MAPTNPSR1ALDH1A1 | |
| SCHEMBL18473339 | 0.71 | ACHE (0.47) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4644475 | 0.70 | MAOA (0.46) | MAOAMAOBCYP1A2CYP2A6MAPT | |
| SCHEMBL12415332 | 0.70 | TNKS (0.40) | ALDH1A1LMNATP53SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292770-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2022-04-05 | — | — | US | disclosed |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292770-B2 | Pyridazinone herbicides | PRDX6, PRDX4, PDXK | MAOA 411/4885MAOB 301/4885CYP1A2 11/4885 |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX6, PRDX4, CHRM2 | MAOA 530/4885MAOB 335/4885CYP1A2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.