Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22795386 | 0.79 | SIGMAR1 (0.42) | CYP1A2L3MBTL1NOTUMCYP3A4CYP2D6 | |
| SCHEMBL18937415 | 0.77 | DDB1 (0.40) | FDPSCYP1A2NOTUMCOMTHTT | |
| SCHEMBL21859333 | 0.74 | INMT (0.40) | CYP1A2L3MBTL1NOTUMALOX15BCYP3A4 | |
| SCHEMBL24885968 | 0.66 | LPO (0.32) | — | |
| SCHEMBL12534008 | 0.63 | ATM (0.41) | CYP1A2L3MBTL1NOTUMALOX15BCYP3A4 | |
| SCHEMBL12040840 | 0.63 | ATM (0.45) | CYP1A2FGFR1NOTUMCYP3A4GAA | |
| SCHEMBL14518808 | 0.61 | PDE4A (0.44) | FDPSCYP1A2L3MBTL1ALOX15BCYP3A4 | |
| SCHEMBL17211130 | 0.61 | INMT (0.44) | CYP1A2L3MBTL1NOTUMCYP3A4CYP2C9 | |
| SCHEMBL17660251 | 0.60 | ELANE (0.41) | CYP1A2COMTALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28230658 | 0.60 | PDE4A (0.43) | FDPSCYP1A2L3MBTL1ALOX15BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844044-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | FDPS 3055/4885CYP1A2 4254/4885FGFR1 3623/4885 |
| US-10844044-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | FDPS 3088/4885CYP1A2 4276/4885FGFR1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.