Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21859333 | 0.84 | INMT (0.40) | SIGMAR1ATMDDB1CRBNSMN1; SMN2 | |
| SCHEMBL21859458 | 0.79 | FDPS (0.34) | SIGMAR1ATMDDB1CRBNSMN1; SMN2 | |
| SCHEMBL17211130 | 0.74 | INMT (0.44) | SIGMAR1ATMDDB1CRBNSMN1; SMN2 | |
| SCHEMBL14797462 | 0.72 | DDB1 (0.52) | ATMDDB1CRBNSMN1; SMN2KDM4E | |
| SCHEMBL11472166 | 0.69 | DDB1 (0.39) | SIGMAR1ATMDDB1CRBNSMN1; SMN2 | |
| SCHEMBL30763485 | 0.69 | DDB1 (0.48) | SIGMAR1ATMDDB1CRBNSMN1; SMN2 | |
| SCHEMBL4228171 | 0.67 | DDB1 (0.42) | ATMDDB1CRBNSMN1; SMN2KDM4E | |
| SCHEMBL20062013 | 0.65 | KDM4E (0.43) | ATMDDB1CRBNSMN1; SMN2KDM4E | |
| SCHEMBL143175 | 0.65 | ALDH1A1 (0.54) | ATMDDB1CRBNSMN1; SMN2KDM4E | |
| SCHEMBL7133435 | 0.64 | GSK3A (0.48) | ATMDDB1CRBNSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392259-A1 | ORTHOMETALLATED CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND COPOLYMERIZATION | ARZOUMANIDIS GREGORY G (US) | 2020-12-17 | — | — | US | disclosed |