Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21832102 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTTSHRCYP2C19DUT | |
| SCHEMBL21832123 | 0.84 | CYP3A4 (0.37) | ALDH1A1MAPTTSHRCYP2C19 | |
| SCHEMBL21859488 | 0.84 | CYP3A4 (0.37) | ALDH1A1MAPTTSHRCYP2C19 | |
| SCHEMBL24420699 | 0.76 | DUT (0.33) | DUT | |
| SCHEMBL22639340 | 0.76 | DUT (0.33) | DUT | |
| SCHEMBL22639184 | 0.76 | DUT (0.33) | DUT | |
| SCHEMBL21859491 | 0.76 | — | — | |
| SCHEMBL21832122 | 0.76 | — | — | |
| SCHEMBL21698858 | 0.74 | DUT (0.31) | DUT | |
| SCHEMBL21859500 | 0.70 | TOP2A (0.31) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200093132-A1 | Methods Of Making Pyranopyrans Such As Pyranopyran Nitrile And Methods of Using Pyranopyrans Such As Pyranopyran Nitrile | VILLANOVA UNIVERSITY | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200093132-A1 | Methods Of Making Pyranopyrans Such As Pyranopyran Nitrile And Methods of Using Pyranopyrans Such As Pyranopyran Nitrile | CBR1, NOX1, NOX3 | ALDH1A1 419/4885MAPT 4150/4885TSHR 1811/4885 |
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | CBR1, NOX1, NOX3 | ALDH1A1 419/4885MAPT 4150/4885TSHR 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.