SCHEMBL218608

SCHEMBL218608

Oc1ccc2c(c1)C1(CC2)CCc2ccc(O)cc21

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
OPRM1 P35372 3/20 0.43
OPRD1 P41143 3/20 0.43
OPRK1 P41145 3/20 0.43
ESR1 P03372 5/20 0.42
ESR2 Q92731 5/20 0.42
PBRM1 Q86U86 1/20 0.41
POLA1 P09884 2/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29646235 1.00 ALDH1A1 (0.44) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL29646238 1.00 ALDH1A1 (0.44) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL14515033 0.89 ALDH1A1 (0.41) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL29646250 0.84 ESR2 (0.53) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL215429 0.84 ESR2 (0.53) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL23715026 0.82 OPRM1 (0.39) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL25191477 0.82 ALDH1A1 (0.42) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL895612 0.78 ALDH1A1 (0.41) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL4236973 0.78 ALDH1A1 (0.49) ALDH1A1LMNACYP3A4OPRM1OPRD1
SCHEMBL5809338 0.74 MAPT (0.41) ALDH1A1CYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1768943-B1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES IND TECH RES INST (CN) 2008-12-17 EP claimed
US-7303855-B2 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-12-04 US claimed
US-7214834-B2 Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives EASTMAN KODAK COMPANY (US) 2007-05-08 US claimed
EP-1768943-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES EASTMAN KODAK COMPANY (US) 2007-04-04 EP claimed
WO-2006019663-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES EASTMAN KODAK COMPANY (US) 2006-02-23 WO claimed
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives EASTMAN KODAK COMPANY 2006-01-26 US claimed
US-20060019195-A1 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-01-26 US claimed
EP-1318971-B1 METHOD FOR RECOVERING MATERIAL VALUES FROM BISPHENOL TARS GEN ELECTRIC (US) 2006-01-11 EP claimed
EP-1318971-A1 METHOD FOR RECOVERING MATERIAL VALUES FROM BISPHENOL TARS GENERAL ELECTRIC COMPANY (US) 2003-06-18 EP claimed
WO-2002022531-A1 METHOD FOR RECOVERING MATERIAL VALUES FROM BISPHENOL TARS GENERAL ELECTRIC COMPANY (US) 2002-03-21 WO claimed
US-6303835-B1 SPARGING THE FLUIDIZED BPA TAR WHILE HEATING IN THE PRESENCE OF A BASIC CATALYST. GENERAL ELECTRIC COMPANY 2001-10-16 US claimed
US-12379663-B2 Material for forming organic film, patterning process, and polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-05 US disclosed
US-20240242967-A1 Polymer For Forming Metal-Containing Film, Composition For Forming Metal-Containing Film, And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
EP-4398037-A1 COMPOUND FOR FORMING METAL-CONTAINING FILM, COMPOSITION FOR FORMING METAL-CONTAINING FILM, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-10 EP disclosed
US-12032293-B2 Composition for forming organic film, patterning process, and polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-09 US disclosed
WO-2005092951-A1 A POLYCARBONATE COMPOSITION AND METHOD OF MAKING THEREOF GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-10-06 WO disclosed
EP-1318971-A1 METHOD FOR RECOVERING MATERIAL VALUES FROM BISPHENOL TARS GENERAL ELECTRIC COMPANY (US) 2003-06-18 EP disclosed
WO-2002022531-A1 METHOD FOR RECOVERING MATERIAL VALUES FROM BISPHENOL TARS GENERAL ELECTRIC COMPANY (US) 2002-03-21 WO disclosed
US-6303835-B1 SPARGING THE FLUIDIZED BPA TAR WHILE HEATING IN THE PRESENCE OF A BASIC CATALYST. GENERAL ELECTRIC COMPANY 2001-10-16 US disclosed
EP-0182486-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives HSD11B1, PKD1, REN ALDH1A1 102/4885LMNA 1923/4885CYP3A4 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.