Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864826 | 0.77 | ALOX5 (0.54) | NPC1RAB9AALOX5MEN1KMT2A | |
| SCHEMBL31574614 | 0.75 | L3MBTL1 (0.55) | ALOX5CYP3A4L3MBTL1 | |
| SCHEMBL21864972 | 0.74 | AOC2 (0.49) | MAOB | |
| SCHEMBL7595917 | 0.73 | LMNA (0.60) | NPC1RAB9AMEN1KMT2AMAOB | |
| SCHEMBL9431017 | 0.70 | MAOB (0.49) | NPC1RAB9AALOX5MEN1KMT2A | |
| SCHEMBL3314513 | 0.70 | ALOX5 (0.59) | NPC1RAB9AALOX5MEN1KMT2A | |
| SCHEMBL19068931 | 0.70 | MAOB (0.51) | NPC1ALOX5MEN1KMT2AMAOB | |
| SCHEMBL14769659 | 0.69 | PDGFRB (0.57) | NPC1RAB9AALOX5MEN1KMT2A | |
| SCHEMBL14925312 | 0.69 | PPARD (0.51) | NPC1RAB9AALOX5MEN1KMT2A | |
| SCHEMBL6584828 | 0.68 | MAOB (0.53) | NPC1RAB9AALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063854-A1 | QUINOLINE-BASED DERIVATIVES AS VAP-1 INHIBITORS | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |