Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865570 | 0.89 | AHCY (0.40) | AHCYMCOLN3ALDH1A1KDM4EGAA | |
| SCHEMBL29835191 | 0.89 | ABL1 (0.46) | ABL1POLBMCOLN3ALDH1A1NR4A2 | |
| SCHEMBL21865383 | 0.84 | AHCY (0.41) | AHCYALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL21865632 | 0.83 | PSEN1 (0.45) | AHCY | |
| SCHEMBL21865385 | 0.83 | AHCY (0.40) | ABL1AHCYALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL3532872 | 0.83 | MAPT (0.41) | ABL1POLBMCOLN3ALDH1A1NR4A2 | |
| SCHEMBL21865761 | 0.82 | AHCY (0.40) | AHCYALDH1A1GLACYP3A4HTT | |
| SCHEMBL21865562 | 0.80 | ALDH1A1 (0.41) | ABL1AHCYPOLBALDH1A1KDM4E | |
| SCHEMBL21865760 | 0.80 | AHCY (0.39) | AHCYALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL28371791 | 0.77 | CYP3A4 (0.44) | MCOLN3ALDH1A1KDM4EGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |