Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131708 | 0.87 | TDP1 (0.61) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL8349258 | 0.83 | EGFR (0.49) | AKR1B1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL502877 | 0.80 | AKR1B1 (0.58) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL12936006 | 0.80 | TDP1 (0.58) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL9394407 | 0.78 | ALDH1A1 (0.56) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL14365382 | 0.78 | EGFR (0.48) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3360138 | 0.77 | DAO (0.49) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL72309 | 0.76 | AKR1B1 (1.00) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL30449014 | 0.76 | AKR1B1 (1.00) | AKR1B1TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL18253321 | 0.76 | HSPA5 (0.50) | TDP1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358686-B2 | Leather or leather article and method for producing same, hexavalent chromium treatment agent, method for treating hexavalent chromium in crude leather or crude leather article | CITIZEN WATCH CO., LTD. (JP) | 2019-07-23 | — | — | US | disclosed |
| EP-2476713-B1 | Resist underlayer film composition and patterning process using the same | SHINETSU CHEMICAL CO (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-20170233835-A1 | LEATHER OR LEATHER ARTICLE AND METHOD FOR PRODUCING SAME, HEXAVALENT CHROMIUM TREATMENT AGENT, METHOD FOR TREATING HEXAVALENT CHROMIUM IN CRUDE LEATHER OR CRUDE LEATHER ARTICLE | CITIZEN WATCH CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3178947-A1 | LEATHER OR LEATHER ARTICLE AND METHOD FOR PRODUCING SAME, HEXAVALENT CHROMIUM TREATMENT AGENT, METHOD FOR TREATING HEXAVALENT CHROMIUM IN CRUDE LEATHER OR CRUDE LEATHER ARTICLE | Citizen Watch Co., Ltd. (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-2816409-B1 | Method for forming a resist under layer film and patterning process | SHINETSU CHEMICAL CO (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| EP-2816409-A1 | Method for forming a resist under layer film and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-20140335692-A1 | METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-13 | — | — | US | disclosed |
| US-8877422-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8853031-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-7081472-B2 | Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them | K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-07-25 | — | — | US | disclosed |
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| US-20040241577-A1 | Resist lower layer film material and method for forming a pattern | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040053911-A1 | Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2004-03-18 | — | — | US | disclosed |
| EP-1343758-A1 | SUBSTITUTED BIS-INDOLE DERIVATIVES USEFUL AS CONTRAST AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES FOR PRODUCING THEM | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002038546-A1 | SUBSTITUTED BIS-INDOLE DERIVATIVES USEFUL AS CONTRAST AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES FOR PRODUCING THEM | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2002-05-16 | — | — | WO | disclosed |
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | disclosed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358686-B2 | Leather or leather article and method for producing same, hexavalent chromium treatment agent, method for treating hexavalent chromium in crude leather or crude leather article | HACL2, LDHA, LCT | AKR1B1 318/4885TDP1 2302/4885KDM4E 768/4885 |
| US-20040053911-A1 | Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them | IDO1, IDO2, CNR1 | AKR1B1 2239/4885TDP1 2398/4885KDM4E 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.