SCHEMBL29131708

SCHEMBL29131708

O=C(O)Cc1cc2ccccc2cc1CC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
KDM4E B2RXH2 3/20 0.59
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
AKR1B1 P15121 2/20 0.58
CAMK2A Q9UQM7 1/20 0.49
PTPN7 P35236 1/20 0.47
PTGS1 P23219 2/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 1/20 0.45
CASP6 P55212 1/20 0.45
ABCC4 O15439 1/20 0.45
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
NR1H4 Q96RI1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12936006 0.92 TDP1 (0.58) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL218722 0.87 AKR1B1 (0.61) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL9394407 0.86 ALDH1A1 (0.56) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL27503589 0.81 HSD17B10 (0.63) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL1629133 0.80 TDP1 (0.70) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL29706153 0.80 TDP1 (0.70) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL29410826 0.79 AKR1B1 (0.76) TDP1KDM4EAKR1B1PTGS1GAA
SCHEMBL30359 0.79 AKR1B1 (0.76) TDP1KDM4EAKR1B1PTGS1GAA
SCHEMBL29048386 0.79 AKR1B1 (0.52) TDP1KDM4EALDH1A1MEN1KMT2A
SCHEMBL3423595 0.79 MEN1 (0.41) TDP1KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813473-A Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-09-29 CN claimed
CN-116813473-B Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-12-08 CN disclosed
CN-116813473-A Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-09-29 CN disclosed