Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL217506 | 0.89 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL217523 | 0.79 | HTR1A (0.36) | ADRA2CCYP17A1CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9016935 | 0.79 | ADRA2C (0.34) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL4057297 | 0.76 | MEN1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8467199 | 0.75 | CHRNB2 (0.34) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL2567611 | 0.75 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5616595 | 0.74 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL5603824 | 0.74 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL218502 | 0.74 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL2568113 | 0.74 | GPR3 (0.31) | GPR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088867-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-01-03 | — | — | US | claimed |
| JP-6240041-A | — | — | None | — | — | JP | disclosed |
| US-20200079944-A1 | COMPOSITION, PELLET, AND PROCESSES OF MAKING POLYPROPYLENE FOAMS | LCY CHEMICAL CORP (TW) | 2020-03-12 | — | — | US | disclosed |
| EP-3130613-A1 | PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST | Idemitsu Kosan Co., Ltd (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-2093268-B1 | PRESSURE-SENSITIVE ADHESIVE SHEET | NITTO DENKO CORP (JP) | 2015-03-25 | — | — | EP | disclosed |
| EP-1558655-B1 | MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM | EXXONMOBIL CHEM PATENTS INC (US) | 2012-08-29 | — | — | EP | disclosed |
| EP-2123459-B1 | Ink reservoir | CANON KK (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-8088867-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2385080-A1 | POLYPROPYLENE RESIN PRE-FOAMED PARTICLE AND METHOD FOR PRODUCING SAME, AND POLYPROPYLENE RESIN IN-MOLD FOAMING MOLDED ARTICLE | Kaneka Corporation (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7662895-B2 | comprising polypropylene which is produced in presence of a metallocene transition metal catalyst and an activator; peak melting point temperature below about 110 degrees C., a tensile set of 40% or less, and greater than or equal to about 60% [r]dyads | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-16 | — | — | US | disclosed |
| EP-1114832-A1 | Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-20010007007-A1 | Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-05 | — | — | US | disclosed |
| WO-2001032757-A1 | FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6110858-A | AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND | TOSOH CORPORATION (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0962474-A1 | Propylene block copolymer and resin composition | Japan Polychem Corporation (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5866706-A | Preparation and separation of RAC and MESO compound mixtures | BOULDER SCIENTIFIC CO. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0849292-A1 | Olefin polymerisation catalysts and processes for producing olefin polymers | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5744535-A | LARGE AND THIN BUMPERS; ETHYLENE-ALPHA OLEFIN COPOLYMERS | UBE INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0769525-A1 | Polypropylene resin composition for exterior parts of automobile | UBE INDUSTRIES LIMITED (JP) | 1997-04-23 | — | — | EP | disclosed |
| JP-H06240041-A | EXPANDED POLYPROPYLENE RESIN PARTICLE | MITSUBISHI YUKA BADISCHE CO LTD | 1994-08-30 | — | — | JP | disclosed |