Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698603 | 0.85 | HTR1F (0.39) | MAPK1PPARGHRH2HTR2AHRH1 | |
| SCHEMBL27698605 | 0.83 | PPARG (0.36) | CYP3A4TSHRMAPK1L3MBTL1PPARG | |
| SCHEMBL2186625 | 0.82 | MAPT (0.56) | LMNAALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL27679675 | 0.81 | LMNA (0.50) | LMNAALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL2187029 | 0.80 | L3MBTL1 (0.46) | LMNAALOX15TSHRMAPK1L3MBTL1 | |
| SCHEMBL2188722 | 0.80 | KDM4E (0.57) | CYP3A4LMNAALOX15TSHRMAPK1 | |
| SCHEMBL2186974 | 0.80 | CACNA2D1 (0.48) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2187333 | 0.80 | MAPT (0.51) | LMNAALOX15TSHRL3MBTL1POLB | |
| SCHEMBL2187555 | 0.79 | MEN1 (0.50) | CYP3A4LMNAPOLBSMN1; SMN2ME2 | |
| SCHEMBL2188442 | 0.78 | NPC1 (0.47) | LMNAALOX15TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |