Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | INMT | O95050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234144 | 0.75 | KMT2A (0.62) | CHRNA7ALDH1A1LMNARECQLKMT2A | |
| SCHEMBL234143 | 0.75 | KMT2A (0.62) | CHRNA7ALDH1A1LMNARECQLKMT2A | |
| SCHEMBL10026155 | 0.75 | KMT2A (0.62) | CHRNA7ALDH1A1LMNARECQLKMT2A | |
| Descyanothiacloprid SCHEMBL1556829 | 0.73 | CHRNA7 (1.00) | CHRNA1CHRNA7KMT2ASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL10463854 | 0.73 | ALDH1A1 (0.44) | CHRNA1CHRNA7ALDH1A1LMNARECQL | |
| SCHEMBL14492891 | 0.72 | LMNA (0.43) | CHRNA1CHRNA7ALDH1A1LMNARECQL | |
| SCHEMBL14931801 | 0.72 | CHRNA7 (0.64) | CHRNA1CHRNA7ALDH1A1LMNAKMT2A | |
| SCHEMBL7507814 | 0.70 | CHRNA7 (0.68) | CHRNA1CHRNA7ALDH1A1LMNAKMT2A | |
| SCHEMBL14931795 | 0.70 | CHRNA7 (0.61) | CHRNA1CHRNA7LMNAKMT2AMAPT | |
| SCHEMBL14270480 | 0.70 | LMNA (0.41) | ALDH1A1LMNARECQLKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198803-C | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | FIRST SUNTORY PHARMACEUTICAL L (JP) | 2005-04-27 | — | — | CN | claimed |
| CN-1349506-A | Heterocyclic compounds having effect of activating nicoting acetylchloine alpha 4 beta 2 receptor | SUNTORY LTD (JP) | 2002-05-15 | — | — | CN | claimed |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | SUNTORY LIMITED | 2002-03-07 | — | — | US | claimed |
| EP-1176141-A1 | HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE $g(a)4$g(b)2 RECEPTOR | SUNTORY LIMITED (JP) | 2002-01-30 | — | — | EP | claimed |
| EP-2305658-B9 | NOVEL IMINO DERIVATIVE, PROCESS FOR PRODUCTION OF THE SAME, AND PESTICIDE COMPRISING THE SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-04-29 | — | — | EP | disclosed |
| EP-2305658-B1 | NOVEL IMINO DERIVATIVE, PROCESS FOR PRODUCTION OF THE SAME, AND PESTICIDE COMPRISING THE SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2014-12-17 | — | — | EP | disclosed |
| EP-2591673-A1 | PEST CONTROL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-8309733-B2 | Imino derivatives, methods for producing the same and insecticides containing the same | Meji Seika Pharma Co., Ltd. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| CN-102076673-A | Novel imino derivative, process for production of same, and pesticide comprising same | KUREHA CORP | 2011-05-25 | — | — | CN | disclosed |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | SUNTORY LIMITED | 2002-03-07 | — | — | US | disclosed |
| EP-1176141-A1 | HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE $g(a)4$g(b)2 RECEPTOR | SUNTORY LIMITED (JP) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | CNOT9, CBR1, CBR3 | CHRNA1 23/4885CHRNA7 125/4885ALDH1A1 1181/4885 |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | CHRNA2, CHRNA7, CHRNB2 | CHRNA1 6/4885CHRNA7 2/4885ALDH1A1 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.