Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24342132 | 0.89 | CTSB (0.39) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL26154352 | 0.83 | REN (0.45) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL23680222 | 0.82 | CTSS (0.41) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL24183746 | 0.81 | OPRD1 (0.45) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL24999273 | 0.80 | CTSS (0.43) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL27354682 | 0.80 | CTSB (0.48) | OPRD1OPRM1OPRK1CTSBCTSL | |
| SCHEMBL24341294 | 0.79 | OPRD1 (0.42) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL24342131 | 0.79 | REN (0.42) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL23680126 | 0.79 | CTSB (0.39) | OPRD1OPRM1OPRK1RENCTSB | |
| SCHEMBL23680114 | 0.79 | REN (0.41) | OPRD1OPRM1OPRK1RENCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063673-A1 | ANTI-B7H3 ANTIBODY-EXATECAN ANALOG CONJUGATE AND MEDICINAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-04-02 | — | — | WO | disclosed |