Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24183746 | 0.87 | OPRD1 (0.45) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL27354682 | 0.86 | CTSB (0.48) | CTSBCTSSCTSLOPRD1OPRM1 | |
| SCHEMBL25045555 | 0.85 | CTSS (0.51) | CTSBCTSSCTSLOPRD1OPRM1 | |
| SCHEMBL24999273 | 0.84 | CTSS (0.43) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL24183741 | 0.83 | CHRNA1 (0.42) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL21882002 | 0.83 | OPRD1 (0.43) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL23680114 | 0.83 | REN (0.41) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL26346709 | 0.82 | PSMB5 (0.50) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL24341294 | 0.81 | OPRD1 (0.42) | RENCTSBCTSSCTSLOPRD1 | |
| SCHEMBL25976646 | 0.81 | OPRM1 (0.42) | RENCTSBCTSSCTSLOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088235-A1 | EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |