SCHEMBL21885250

SCHEMBL21885250

c1ccc(-c2ccccc2-c2ccc(N(c3ccc(-c4cccc5c6ccccc6c6c(-c7ccccc7)c7ccccc7n6c45)cc3)c3ccc4c(c3)oc3ccccc34)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
AHR P35869 1/20 0.31
ALOX5 P09917 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21885239 0.99 MEN1 (0.33) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885340 0.96 MEN1 (0.32) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885310 0.94 MMP12 (0.32) MEN1KMT2AAHRALOX5KDM4E
SCHEMBL21885031 0.93 MEN1 (0.33) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885338 0.91 MEN1 (0.31) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885339 0.90 PLA2G2A (0.31) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885321 0.89 MEN1 (0.32) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885687 0.87 MEN1 (0.31) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885312 0.86 PLA2G2A (0.34) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21885039 0.86 MAPK14 (0.31) KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE MAOA, PNMT, TPH1 MEN1 1265/4885KMT2A 1236/4885THRB 2037/4885
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device MAOA, PNMT, TPH1 MEN1 1265/4885KMT2A 1236/4885THRB 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.